Interactive XCMS Online: simplifying advanced metabolomic data processing and subsequent statistical analyses
XCMS Online (xcmsonline. scripps. edu) is a cloud-based informatic platform designed to
process and visualize mass-spectrometry-based, untargeted metabolomic data. Initially, the …
process and visualize mass-spectrometry-based, untargeted metabolomic data. Initially, the …
Chemical discovery in the era of metabolomics
M Sindelar, GJ Patti - Journal of the American Chemical Society, 2020 - ACS Publications
Untargeted metabolomics aims to quantify the complete set of metabolites within a biological
system, most commonly by liquid chromatography/mass spectrometry (LC/MS). Since nearly …
system, most commonly by liquid chromatography/mass spectrometry (LC/MS). Since nearly …
HILIC‐MS for metabolomics: An attractive and complementary approach to RPLC‐MS
Hydrophilic interaction chromatography (HILIC) is an emerging separation mode of liquid
chromatography (LC). Using highly hydrophilic stationary phases capable of retaining …
chromatography (LC). Using highly hydrophilic stationary phases capable of retaining …
Ion mobility derived collision cross sections to support metabolomics applications
Metabolomics is a rapidly evolving analytical approach in life and health sciences. The
structural elucidation of the metabolites of interest remains a major analytical challenge in …
structural elucidation of the metabolites of interest remains a major analytical challenge in …
Untargeted LC/MS-based metabolic phenotyping (metabonomics/metabolomics): The state of the art
Liquid chromatography (LC) hyphenated to mass spectrometry is currently the most widely
used means of determining metabolic phenotypes via both untargeted and targeted …
used means of determining metabolic phenotypes via both untargeted and targeted …
Biomonitoring in the era of the exposome
Background: The term “exposome” was coined in 2005 to underscore the importance of the
environment to human health and to bring research efforts in line with those on the human …
environment to human health and to bring research efforts in line with those on the human …
Can NMR solve some significant challenges in metabolomics?
The field of metabolomics continues to witness rapid growth driven by fundamental studies,
methods development, and applications in a number of disciplines that include biomedical …
methods development, and applications in a number of disciplines that include biomedical …
The blood exposome and its role in discovering causes of disease
Background: Since 2001, researchers have examined the human genome (G) mainly to
discover causes of disease, despite evidence that G explains relatively little risk. We posit …
discover causes of disease, despite evidence that G explains relatively little risk. We posit …
Optimized Analytical Procedures for the Untargeted Metabolomic Profiling of Human Urine and Plasma by Combining Hydrophilic Interaction (HILIC) and Reverse …
K Contrepois, L Jiang, M Snyder - Molecular & Cellular Proteomics, 2015 - ASBMB
Profiling of body fluids is crucial for monitoring and discovering metabolic markers of health
and disease and for providing insights into human physiology. Since human urine and …
and disease and for providing insights into human physiology. Since human urine and …
[HTML][HTML] Neisseria species as pathobionts in bronchiectasis
L Li, M Mac Aogain, T Xu, TK Jaggi, LLY Chan, J Qu… - Cell host & …, 2022 - cell.com
Neisseria species are frequently identified in the bronchiectasis microbiome, but they are
regarded as respiratory commensals. Using a combination of human cohorts, next …
regarded as respiratory commensals. Using a combination of human cohorts, next …