BACKGROUND Since the 1998 European Respiratory Society (ERS) lower respiratory tract
infection (LRTI) guidelines 1 were published, the evidence on which they were based has …

Clin Microbiol Infect 2011; 17 (Suppl. 6): E1–E59 Abstract This document is an update of
Guidelines published in 2005 and now includes scientific publications through to May 2010 …

Objectives Data on quinolone consumption in the community were collected from 30
EU/European Economic Area (EEA) countries over two decades. This article reviews …

The Infectious Diseases Society of America (IDSA) produced guidelines for community-
acquired pneumonia (CAP) in immunocompetent adults in 1998 and again in 2000 [1, 2] …

Background: We investigated whether the use of respiratory fluoroquinolones was
associated with better clinical outcomes compared with the use of macrolides and β-lactams …

Interest in abnormal breathing after stroke has a long history dating back at least to the
observations of John Cheyne in 1818. 1 In recent years this interest has been reawakened …

Background Although fluoroquinolones possess excellent in vitro activity against Legionella,
few large-scale clinical trials have examined their efficacy in the treatment of Legionnaires …

Study objectives To evaluate the efficacy and tolerability of levofloxacin (L) as monotherapy
in patients with severe community-acquired pneumonia (CAP) in comparison with therapy …

Introduction: Fluoroquinolone use has dramatically increased since the introduction of the
first respiratory fluoroquinolone in the late 1990s. Levofloxacin, like other fluoquinolones, is …

Background Tigecycline, an expanded broad-spectrum glycylcycline, exhibits in vitro activity
against many common pathogens associated with community-acquired pneumonia (CAP) …