Sequence analysis of SARS-CoV-2 Delta variant isolated from Makassar, South Sulawesi, Indonesia

MN Massi, R Sjahril, H Halik, GV Soraya, N Hidayah… - Heliyon, 2023 - cell.com
Introduction This study aimed to perform mutation and phylogenetic analyses of the Severe
Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Delta variants and analyze the …

Chronicling the 3-year evolution of the COVID-19 pandemic: Analysis of disease management, characteristics of major variants, and impacts on pathogenicity

E Pitsillou, Y Yu, RC Beh, JJ Liang, A Hung… - Clinical and …, 2023 - Springer
Abstract Announced on December 31, 2019, the novel coronavirus arising in Wuhan City,
Hubei Province resulted in millions of cases and lives lost. Following intense tracking …

Design of human ACE2 mimic miniprotein binders that interact with RBD of SARS-CoV-2 variants of concerns

NK Gaur, Z Khakerwala, RD Makde - Journal of Biomolecular …, 2024 - Taylor & Francis
The world of medicine demands from the research community solutions to the emerging
problem of SARS-CoV-2 variants and other such potential global pandemics. With …

Low-Entropy Hydration Shells at the Spike RBD's Binding Site May Reveal the Contagiousness of SARS-CoV-2 Variants

L Yang, S Guo, C Hou, S Jiang, L Shi, X Ma, B Zheng… - Biomolecules, 2023 - mdpi.com
The infectivity of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is
primarily determined by the binding affinity between the receptor-binding domain (RBD) of …

Identifications of novel host cell factors that interact with the receptor-binding domain of the SARS-CoV-2 spike protein

X Tang, Y Liu, J Wang, T Long, BWY Mok… - Journal of Biological …, 2024 - ASBMB
SARS-CoV-2 entry into host cells is facilitated by the interaction between the receptor-
binding domain of its spike protein (CoV2-RBD) and host cell receptor, ACE2, promoting …

Dual mechanism: Epigenetic inhibitor apabetalone reduces SARS-CoV-2 Delta and Omicron variant spike binding and attenuates SARS-CoV-2 RNA induced …

L Fu, D Gilham, SC Stotz, CD Sarsons, BD Rakai… - International …, 2023 - Elsevier
The SARS-CoV-2 virus initiates infection via interactions between the viral spike protein and
the ACE2 receptors on host cells. Variants of concern have mutations in the spike protein …

Exploring Conformational Landscapes and Binding Mechanisms of Convergent Evolution for the SARS-CoV-2 Spike Omicron Variant Complexes with the ACE2 …

N Raisinghani, M Alshahrani, G Gupta… - Physical Chemistry …, 2024 - pubs.rsc.org
In this study, we combined AlphaFold-based approaches for atomistic modeling of multiple
protein states and microsecond molecular simulations to accurately characterize …

Ensemble-Based Mutational Profiling and Network Analysis of the SARS-CoV-2 Spike Omicron XBB Lineages for Interactions with the ACE2 Receptor and Antibodies …

N Raisinghani, M Alshahrani, G Gupta… - International Journal of …, 2024 - mdpi.com
In this study, we performed a computational study of binding mechanisms for the SARS-CoV-
2 spike Omicron XBB lineages with the host cell receptor ACE2 and a panel of diverse class …

Single-photon scattering in giant-atom waveguide systems with chiral coupling

SY Li, ZQ Zhang, L Du, Y Li, H Wu - Physical Review A, 2024 - APS
We study single-photon scattering spectra of a giant atom chirally coupled to a one-
dimensional waveguide at multiple connection points, and examine chirality-induced effects …

A within-host model of SARS-CoV-2 infection

J Carruthers, J Xu, T Finnie, I Hall - MedRxiv, 2022 - medrxiv.org
Within-host models have been used to successfully describe the dynamics of multiple viral
infections, however, the dynamics of SARS-CoV-2 virus infection remain poorly understood …