Three-dimensional visualization of viral structure, entry, and replication underlying the spread of SARS-CoV-2

JW Saville, AM Berezuk, SS Srivastava… - Chemical …, 2022 - ACS Publications
The global spread of SARS-CoV-2 has proceeded at an unprecedented rate. Remarkably,
characterization of the virus using modern tools in structural biology has also progressed at …

Lung epithelial and endothelial damage, loss of tissue repair, inhibition of fibrinolysis, and cellular senescence in fatal COVID-19

F D'Agnillo, KA Walters, Y Xiao, ZM Sheng… - Science translational …, 2021 - science.org
Coronavirus disease 2019 (COVID-19), caused by the severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2), is characterized by respiratory distress, multiorgan …

Corticosteroids in COVID-19: pros and cons

A Bahsoun, Y Fakih, R Zareef, F Bitar, M Arabi - Frontiers in Medicine, 2023 - frontiersin.org
The wide and rapid spread of the COVID-19 pandemic has placed an unanticipated burden
on the global healthcare sector. This necessitated a swift response from the international …

[HTML][HTML] Efficacy of favipiravir in adults with mild COVID-19: a randomized, double-blind, multicentre, placebo-controlled clinical trial

M Bosaeed, A Alharbi, E Mahmoud, S Alrehily… - Clinical Microbiology …, 2022 - Elsevier
Objective To evaluate whether favipiravir reduces the time to viral clearance as documented
by negative RT-PCR results for severe acute respiratory syndrome coronavirus 2 in mild …

Factors associated with healthcare workers'(HCWs) acceptance of COVID-19 vaccinations and indications of a role model towards population vaccinations from a …

K Fotiadis, K Dadouli, I Avakian… - International journal of …, 2021 - mdpi.com
A Knowledge, Attitudes and Practices (KAP) study was conducted at the end of May 2021
engaging 1456 healthcare workers (HCWs) from 20 hospitals throughout Greece …

A comprehensive review on the efficacy of several pharmacologic agents for the treatment of COVID-19

F Haddad, G Dokmak, R Karaman - Life, 2022 - mdpi.com
Simple Summary Treatments for coronavirus disease-2019 (COVID-19) have utilized a
variety of medications, including antivirals, immunomodulators, and other therapeutics such …

RIG-I-induced innate antiviral immunity protects mice from lethal SARS-CoV-2 infection

S Marx, BM Kümmerer, C Grützner, H Kato… - … Therapy-Nucleic Acids, 2022 - cell.com
The SARS-CoV-2 pandemic has underscored the need for rapidly usable prophylactic and
antiviral treatments against emerging viruses. The targeted stimulation of antiviral innate …

[HTML][HTML] Adverse events following the first dose of Covishield (ChAdOx1 nCoV-19) vaccination among health workers in selected districts of central and western Nepal …

P Subedi, GK Yadav, B Paudel, A Regmi, P Pyakurel - PLoS One, 2021 - journals.plos.org
Introduction The study aimed at exploring the adverse events following immunization (AEFI)
and their incidences among health workers in three different districts of central and western …

COVID-19 Treatment—Current Status, Advances, and Gap

C Ho, PC Lee - Pathogens, 2022 - mdpi.com
COVID-19, which emerged in December 2019, was declared a global pandemic by the
World Health Organization (WHO) in March 2020. The disease was caused by severe acute …

Data quality considerations for evaluating COVID-19 treatments using real world data: learnings from the National COVID Cohort Collaborative (N3C)

H Sidky, JC Young, AT Girvin, E Lee, YR Shao… - BMC medical research …, 2023 - Springer
Background Multi-institution electronic health records (EHR) are a rich source of real world
data (RWD) for generating real world evidence (RWE) regarding the utilization, benefits and …