Along with the wide use of pesticides in the world, the concerns over their health impacts are
rapidly growing. There is a huge body of evidence on the relation between exposure to …

Bisphenol-A (BPA) is one of the highest volume chemicals produced worldwide, with over 6
billion pounds produced and over 100 t released into the atmosphere each year. Recent …

Diabetes has emerged as an epidemic of the 21st century, and retinopathy remains the
leading cause of blindness in young adults and the mechanism of this blinding disease …

Epigenetic signals are responsible for the establishment, maintenance, and reversal of
metastable transcriptional states that are fundamental for the cell's ability to “remember” past …

While the eukaryotic genome is the same throughout all somatic cells in an organism, there
are specific structures and functions that discern one type of cell from another. These …

Longevity and healthy aging are among the most complex phenotypes studied to date. The
heritability of age at death in adulthood is approximately 25%. Studies of exceptionally long …

Genome instability has long been implicated as the main causal factor in aging. Somatic
cells are continuously exposed to various sources of DNA damage, from reactive oxygen …

Antibiotic resistance has emerged as one of the most pressing, global threats to public
health. In single-species experiments selection for antibiotic resistance occurs at very low …

Background. The genetic contribution to longevity in humans has been estimated to range
from 15% to 25%. Only two genes, APOE and FOXO3, have shown association with …

Cellular stress increases progressively with aging in mammalian tissues. Chronic stress
triggers several signaling cascades that can induce a condition called cellular senescence …