Selenium in bodily homeostasis: hypothalamus, hormones, and highways of communication

P Toh, JL Nicholson, AM Vetter, MJ Berry… - International journal of …, 2022 - mdpi.com
The ability of the body to maintain homeostasis requires constant communication between
the brain and peripheral tissues. Different organs produce signals, often in the form of …

Selenium: From fluorescent probes to biomedical application

J Wang, M Chen, Z Zhang, L Ma, T Chen - Coordination Chemistry Reviews, 2023 - Elsevier
Selenium (Se) is of fundamental importance to human health as an essential trace element,
mainly through regulation of selenoproteins (SePs). Therefore, monitoring Se transformation …

Selenoprotein P concentrations and risk of progression from mild cognitive impairment to dementia

M Vinceti, T Urbano, A Chiari, T Filippini, LA Wise… - Scientific Reports, 2023 - nature.com
There is a growing literature investigating the effects of selenium on the central nervous
system and cognitive function. However, little is known about the role of selenoprotein P, the …

Pilot study of cytoprotective mechanisms of selenium nanorods (SeNrs) under ischemia-like conditions on cortical astrocytes

EG Varlamova, EY Plotnikov, IV Baimler… - International Journal of …, 2023 - mdpi.com
The cytoprotective properties of the trace element selenium, its nanoparticles, and selenium
nanocomplexes with active compounds are shown using a number of models. To date …

Maternal suboptimal selenium intake and low-level lead exposure affect offspring's microglial immune profile and its reactivity to a subsequent inflammatory hit

R De Simone, MA Ajmone-Cat, AM Tartaglione… - Scientific Reports, 2023 - nature.com
Micronutrients such as selenium (Se) are essentials since prenatal life to support brain and
cognitive development. Se deficiency, which affects up to 1 billion people worldwide, can …

A homozygous mutation in the human selenocysteine tRNA gene impairs UGA recoding activity and selenoproteome regulation by selenium

C Vindry, O Guillin, P Wolff, P Marie… - Nucleic Acids …, 2023 - academic.oup.com
Abstract The selenocysteine (Sec) tRNA (tRNA [Ser] Sec) governs Sec insertion into
selenoproteins by the recoding of a UGA codon, typically used as a stop codon. A …

[HTML][HTML] Adherence to the Mediterranean-DASH Intervention for Neurodegenerative Delay (MIND) diet and exposure to selenium species: A cross-sectional study

T Urbano, T Filippini, M Malavolti, S Fustinoni… - Nutrition Research, 2024 - Elsevier
Selenium is a trace element found in many chemical forms. Selenium and its species have
nutritional and toxicologic properties, some of which may play a role in the etiology of …

Selenosugar, selenopolysaccharide, and putative selenoflavonoid in plants

Z Qi, A Duan, K Ng - … Reviews in Food Science and Food …, 2024 - Wiley Online Library
Selenium (Se) is a naturally occurring essential micronutrient that is required for human
health. Selenium supports cellular antioxidant defense and possesses bioeffects such as …

[HTML][HTML] Maternal selenium deficiency during pregnancy in association with autism and ADHD traits in children: The Odense Child Cohort

K Demircan, TS Chillon, RC Jensen, TK Jensen… - Free Radical Biology …, 2024 - Elsevier
Background Selenoproteins regulate pathways controlling neurodevelopment, eg, redox
signaling and thyroid hormone metabolism. However, studies investigating maternal …

Selenium-Containing Agents Acting on Cancer—A New Hope?

S Garbo, S Di Giacomo, D Łażewska… - Pharmaceutics, 2022 - mdpi.com
Selenium-containing agents are more and more considered as an innovative potential
treatment option for cancer. Light is shed not only on the considerable advancements made …