When a calorie is not just a calorie: Diet quality and timing as mediators of metabolism and healthy aging

MM Mihaylova, A Chaix, M Delibegovic, JJ Ramsey… - Cell metabolism, 2023 - cell.com
An epidemic of obesity has affected large portions of the world, increasing the risk of
developing many different age-associated diseases, including cancer, cardiovascular …

[HTML][HTML] Time-restricted eating: Watching the clock to treat obesity

M Ezpeleta, S Cienfuegos, S Lin, V Pavlou, K Gabel… - Cell Metabolism, 2024 - cell.com
Time-restricted eating (TRE) has become a popular strategy to treat obesity. TRE involves
confining the eating window to 4–10 h per day and fasting for the remaining hours (14–20 h …

[HTML][HTML] Feasibility of time-restricted eating and impacts on cardiometabolic health in 24-h shift workers: The Healthy Heroes randomized control trial

ENC Manoogian, A Zadourian, HC Lo, NR Gutierrez… - Cell metabolism, 2022 - cell.com
Over a quarter of the workforce in industrialized countries does shift work, which increases
the risk for cardiometabolic disease. Yet shift workers are often excluded from lifestyle …

[HTML][HTML] Diurnal transcriptome landscape of a multi-tissue response to time-restricted feeding in mammals

S Deota, T Lin, A Chaix, A Williams, H Le, H Calligaro… - Cell metabolism, 2023 - cell.com
Time-restricted feeding (TRF) is an emerging behavioral nutrition intervention that involves a
daily cycle of feeding and fasting. In both animals and humans, TRF has pleiotropic health …

[HTML][HTML] Circadian modulation by time-restricted feeding rescues brain pathology and improves memory in mouse models of Alzheimer's disease

DS Whittaker, L Akhmetova, D Carlin, H Romero… - Cell metabolism, 2023 - cell.com
Circadian disruptions impact nearly all people with Alzheimer's disease (AD), emphasizing
both their potential role in pathology and the critical need to investigate the therapeutic …

Daytime-restricted feeding enhances running endurance without prior exercise in mice

H Xin, R Huang, M Zhou, J Chen, J Zhang, T Zhou… - Nature …, 2023 - nature.com
Physical endurance and energy conservation are essential for survival in the wild. However,
it remains unknown whether and how meal timing regulates physical endurance and muscle …

[HTML][HTML] Metabolic diseases and healthy aging: identifying environmental and behavioral risk factors and promoting public health

K Zhang, Y Ma, Y Luo, Y Song, G Xiong, Y Ma… - Frontiers in Public …, 2023 - frontiersin.org
Aging is a progressive and irreversible pathophysiological process that manifests as the
decline in tissue and cellular functions, along with a significant increase in the risk of various …

[HTML][HTML] Dietary circadian rhythms and cardiovascular disease risk in the prospective NutriNet-Santé cohort

A Palomar-Cros, VA Andreeva, LK Fezeu… - Nature …, 2023 - nature.com
Daily eating/fasting cycles synchronise circadian peripheral clocks, involved in the
regulation of the cardiovascular system. However, the associations of daily meal and fasting …

The effect of early time-restricted eating vs later time-restricted eating on weight loss and metabolic health

J Liu, P Yi, F Liu - The Journal of Clinical Endocrinology & …, 2023 - academic.oup.com
Context It remains controversial whether the choice of the daily eating window early or later
in time-restricted eating (TRE) intervention (early or later TRE) has different effects on weight …

Fasting: from physiology to pathology

D Tang, Q Tang, W Huang, Y Zhang, Y Tian… - Advanced …, 2023 - Wiley Online Library
Overnutrition is a risk factor for various human diseases, including neurodegenerative
diseases, metabolic disorders, and cancers. Therefore, targeting overnutrition represents a …