Ischemia—reperfusion injury of the intestine and protective strategies against injury

IH Mallick, W Yang, MC Winslet… - Digestive diseases and …, 2004 - Springer
Ischemia—Reperfusion injury of the intestine is a significant problem in abdominal aortic
aneurysm surgery, small bowel transplantation, cardiopulmonary bypass, strangulated …

Consequences of brief ischemia: stunning, preconditioning, and their clinical implications: part 1

RA Kloner, RB Jennings - Circulation, 2001 - Am Heart Assoc
In experimental studies in the dog, total proximal coronary artery occlusions of up to 15
minutes result in reversible injury, meaning that the myocytes survive this insult. The 15 …

Sex differences in mortality following acute coronary syndromes

JS Berger, L Elliott, D Gallup, M Roe, CB Granger… - Jama, 2009 - jamanetwork.com
Context Conflicting information exists about whether sex differences modulate short-term
mortality following acute coronary syndromes (ACS). Objectives To investigate the …

GLP-1R agonist liraglutide activates cytoprotective pathways and improves outcomes after experimental myocardial infarction in mice

MH Noyan-Ashraf, MA Momen, K Ban, AM Sadi… - Diabetes, 2009 - Am Diabetes Assoc
OBJECTIVE Glucagon-like peptide-1 receptor (GLP-1R) agonists are used to treat type 2
diabetes, and transient GLP-1 administration improved cardiac function in humans after …

Ischemic tolerance and endogenous neuroprotection

U Dirnagl, RP Simon, JM Hallenbeck - Trends in neurosciences, 2003 - cell.com
Practically any stimulus capable of causing injury to a tissue or organ can, when applied
close to (but below) the threshold of damage, activate endogenous protective mechanisms …

Hearts from rodents exposed to intermittent hypoxia or erythropoietin are protected against ischemia-reperfusion injury

Z Cai, DJ Manalo, G Wei, ER Rodriguez, K Fox-Talbot… - Circulation, 2003 - Am Heart Assoc
Background—Preconditioning phenomena provide evidence for adaptive responses to
ischemia that have important implications for treatment/prevention of myocardial infarction …

Loss of cardioprotection with ageing

K Boengler, R Schulz, G Heusch - Cardiovascular research, 2009 - academic.oup.com
Not only the prevalence, but also the mortality due to ischaemic cardiovascular disease is
higher in older than in young humans, and the demographic shift towards an ageing …

[HTML][HTML] Hypoxic acclimation improves cardiac redox homeostasis and protects heart against ischemia-reperfusion injury through upregulation of O-GlcNAcylation

W Ou, Y Liang, Y Qing, W Wu, M Xie, Y Zhang, Y Zhang… - Redox biology, 2021 - Elsevier
Abstract Ischemia-reperfusion (I/R) injury is detrimental to cardiovascular system. Alteration
in glucose metabolism has been recognized as an important adaptive response under …

Mechanisms of cardioprotection by volatile anesthetics

K Tanaka, LM Ludwig, JR Kersten… - The Journal of the …, 2004 - pubs.asahq.org
A RAPIDLY growing body of evidence indicates that volatile anesthetics protect myocardium
against reversible and irreversible ischemic injury. Identifying the mechanisms by which …

Discovery of a new function of cyclooxygenase (COX)-2: COX-2 is a cardioprotective protein that alleviates ischemia/reperfusion injury and mediates the late phase of …

R Bolli, K Shinmura, XL Tang, E Kodani… - Cardiovascular …, 2002 - academic.oup.com
More than 10 years after its discovery, the function of cyclooxygenase-2 (COX-2) in the
cardiovascular system remains largely an enigma. Many scholars have assumed that the …