Cardiovascular consequences of sleep-disordered breathing: contribution of animal models to understanding of the human disease

M Dematteis, D Godin-Ribuot, C Arnaud, C Ribuot… - ILAR …, 2009 - academic.oup.com
Sleep-disordered breathing, and particularly the highly prevalent obstructive sleep apnea
syndrome, is a multicomponent disorder combining intermittent hypoxia (IH), sleep …

LPS preconditioning attenuates apoptosis mechanism by inhibiting NF-κB and caspase-3 activity: TLR4 pre-activation in the signaling pathway of LPS-induced …

PG Sangaran, ZA Ibrahim, Z Chik, Z Mohamed… - Molecular …, 2021 - Springer
Neuroinflammation, an inflammatory response within the nervous system, has been shown
to be implicated in the progression of various neurodegenerative diseases. Recent in vivo …

Mitochondrial potassium channels and uncoupling proteins in synaptic plasticity and neuronal cell death

MP Mattson, D Liu - Biochemical and biophysical research communications, 2003 - Elsevier
The function of the nervous system relies upon synaptic transmission, a process in which a
neurotransmitter released from pre-synaptic terminals of one neuron (in response to …

Sphingosine kinase activation mediates ischemic preconditioning in murine heart

ZQ Jin, EJ Goetzl, JS Karliner - Circulation, 2004 - Am Heart Assoc
Background—Phosphorylation of sphingosine by sphingosine kinase (SK) is the rate-
limiting step in the cellular synthesis of sphingosine 1-phosphate (S1P). The …

Reduction of early reperfusion injury with the mitochondria-targeting peptide bendavia

DA Brown, SL Hale, CP Baines… - Journal of …, 2014 - journals.sagepub.com
We recently showed that Bendavia, a novel mitochondria-targeting peptide, reduced
infarction and no-reflow across several experimental models. The purpose of this study was …

Remote ischemic conditioning: evolution of the concept, mechanisms, and clinical application

P Saxena, MAJ Newman, JS Shehatha… - Journal of cardiac …, 2010 - Wiley Online Library
Remote ischemic conditioning is a novel concept of protection against ischemia‐reperfusion
injury. Brief controlled episodes of intermittent ischemia of the arm or leg may confer a …

Cardiac ECMO for biventricular hearts after paediatric open heart surgery

RR Chaturvedi, D Macrae, KL Brown, M Schindler… - Heart, 2004 - heart.bmj.com
Objective: To delineate predictors of hospital survival in a large series of children with
biventricular physiology supported with extracorporeal membrane oxygenation (ECMO) after …

Nitroglycerin and delayed preconditioning in humans: yet another new mechanism for an old drug?

G Heusch - Circulation, 2001 - Am Heart Assoc
Short episodes of ischemia and reperfusion protect the myocardium from the damage
induced by episodes of sustained ischemia. Such ischemic preconditioning is apparent …

[HTML][HTML] Non-invasive remote limb ischemic postconditioning protects rats against focal cerebral ischemia by upregulating STAT3 and reducing apoptosis

Z Cheng, L Li, X Mo, L Zhang… - International …, 2014 - spandidos-publications.com
The signal transducer and activator of transcription 3 (STAT3) signaling pathway has been
implicated in cell apoptosis and inflammatory processes. Ischemic preconditioning (IPC) and …

Cardioprotective properties of humoral factors released from rat hearts subject to ischemic preconditioning

FC Serejo, J Luiz Fernando Rodrigues… - Journal of …, 2007 - journals.lww.com
Myocardial protection can be achieved by transfer of coronary effluent from ischemically
preconditioned to non-preconditioned hearts. This study was designed to test the hypothesis …