Machine Learning in RNA Structure Prediction: Advances and Challenges

S Zhang, J Li, SJ Chen - Biophysical Journal, 2024 - cell.com
RNA molecules play a crucial role in various biological processes, with their functionality
closely tied to their structures. The remarkable advancements in machine learning …

[HTML][HTML] ABC2A: A Straightforward and Fast Method for the Accurate Backmapping of RNA Coarse-Grained Models to All-Atom Structures

YZ Shi, H Wu, SS Li, HZ Li, BG Zhang, YL Tan - Molecules, 2024 - mdpi.com
RNAs play crucial roles in various essential biological functions, including catalysis and
gene regulation. Despite the widespread use of coarse-grained (CG) models/simulations to …

[HTML][HTML] lociPARSE: a locality-aware invariant point attention model for scoring RNA 3D structures

S Tarafder, D Bhattacharya - bioRxiv, 2023 - ncbi.nlm.nih.gov
A scoring function that can reliably assess the accuracy of a 3D RNA structural model in the
absence of experimental structure is not only important for model evaluation and selection …

RNA-MobiSeq: Deep mutational scanning and mobility-based selection for RNA structure inference

J Tang, Y Shi, Z Zhang, D Luo, J Zhan, Y Zhou - bioRxiv, 2024 - biorxiv.org
Tertiary structures of RNAs are increasingly found to be essential for their functions and yet
are notoriously challenging to be determined by experimental techniques or predicted by …

On the completeness of existing RNA fragment structures

X Hong, J Zhan, Y Zhou - bioRxiv, 2024 - biorxiv.org
Success in protein structure prediction by the deep learning method AlphaFold 2 naturally
gives arise the question if we can do the same for RNA structure prediction. One reason for …

AI-powered microscopy image analysis for parasitology: integrating human expertise

R Feng, S Li, Y Zhang - Trends in Parasitology, 2024 - cell.com
Microscopy image analysis plays a pivotal role in parasitology research. Deep learning (DL),
a subset of artificial intelligence (AI), has garnered significant attention. However, traditional …