Nsp3 of coronaviruses: Structures and functions of a large multi-domain protein
J Lei, Y Kusov, R Hilgenfeld - Antiviral research, 2018 - Elsevier
The multi-domain non-structural protein 3 (Nsp3) is the largest protein encoded by the
coronavirus (CoV) genome, with an average molecular mass of about 200 kD. Nsp3 is an …
coronavirus (CoV) genome, with an average molecular mass of about 200 kD. Nsp3 is an …
Structure and function of major SARS-CoV-2 and SARS-CoV proteins
SARS-CoV-2 virus, the causative agent of COVID-19 pandemic, has a genomic organization
consisting of 16 nonstructural proteins (nsps), 4 structural proteins, and 9 accessory …
consisting of 16 nonstructural proteins (nsps), 4 structural proteins, and 9 accessory …
A molecular pore spans the double membrane of the coronavirus replication organelle
G Wolff, RWAL Limpens, JC Zevenhoven-Dobbe… - Science, 2020 - science.org
Coronavirus genome replication is associated with virus-induced cytosolic double-
membrane vesicles, which may provide a tailored microenvironment for viral RNA synthesis …
membrane vesicles, which may provide a tailored microenvironment for viral RNA synthesis …
The enzymatic activity of the nsp14 exoribonuclease is critical for replication of MERS-CoV and SARS-CoV-2
NS Ogando, JC Zevenhoven-Dobbe… - Journal of …, 2020 - Am Soc Microbiol
Coronaviruses (CoVs) stand out for their large RNA genome and complex RNA-synthesizing
machinery comprising 16 nonstructural proteins (nsps). The bifunctional nsp14 contains 3 …
machinery comprising 16 nonstructural proteins (nsps). The bifunctional nsp14 contains 3 …
[HTML][HTML] The SARS-coronavirus infection cycle: a survey of viral membrane proteins, their functional interactions and pathogenesis
NA Wong, MH Saier Jr - International journal of molecular sciences, 2021 - mdpi.com
Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2) is a novel epidemic
strain of Betacoronavirus that is responsible for the current viral pandemic, coronavirus …
strain of Betacoronavirus that is responsible for the current viral pandemic, coronavirus …
The intrinsically disordered SARS-CoV-2 nucleoprotein in dynamic complex with its viral partner nsp3a
The processes of genome replication and transcription of SARS-CoV-2 represent important
targets for viral inhibition. Betacoronaviral nucleoprotein (N) is a highly dynamic cofactor of …
targets for viral inhibition. Betacoronaviral nucleoprotein (N) is a highly dynamic cofactor of …
Computational inference of selection underlying the evolution of the novel coronavirus, severe acute respiratory syndrome coronavirus 2
The novel coronavirus severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) that
recently emerged in China is thought to have a bat origin, as its closest known relative …
recently emerged in China is thought to have a bat origin, as its closest known relative …
Structural and functional insights into non-structural proteins of coronaviruses
Coronaviruses (CoVs) are causing a number of human and animal diseases because of
their zoonotic nature such as Middle East respiratory syndrome (MERS), severe acute …
their zoonotic nature such as Middle East respiratory syndrome (MERS), severe acute …
A comprehensive review about SARS-CoV-2
The coronavirus disease (COVID-19) was first identified in China, December 2019. Since
then, it has spread the length and breadth of the world at an unprecedented, alarming rate …
then, it has spread the length and breadth of the world at an unprecedented, alarming rate …
[HTML][HTML] Large scale genomic analysis of 3067 SARS-CoV-2 genomes reveals a clonal geo-distribution and a rich genetic variations of hotspots mutations
In late December 2019, an emerging viral infection COVID-19 was identified in Wuhan,
China, and became a global pandemic. Characterization of the genetic variants of SARS …
China, and became a global pandemic. Characterization of the genetic variants of SARS …