Prospective roles of tumor necrosis factor-alpha (TNF-α) in COVID-19: prognosis, therapeutic and management
Z Mohd Zawawi, J Kalyanasundram… - International journal of …, 2023 - mdpi.com
The coronavirus disease 2019 (COVID-19) became a worldwide concern at the beginning of
2020 and has affected millions. Several previous studies revealed the impact of the …
2020 and has affected millions. Several previous studies revealed the impact of the …
Respiratory and systemic monocytes, dendritic cells, and myeloid‐derived suppressor cells in COVID‐19: Implications for disease severity
S Falck‐Jones, B Österberg… - Journal of Internal …, 2023 - Wiley Online Library
Since the beginning of the SARS‐CoV‐2 pandemic in 2020, researchers worldwide have
made efforts to understand the mechanisms behind the varying range of COVID‐19 disease …
made efforts to understand the mechanisms behind the varying range of COVID‐19 disease …
Macrophage ACE2 is necessary for SARS-CoV-2 replication and subsequent cytokine responses that restrict continued virion release
LI Labzin, KY Chew, K Eschke, X Wang, T Esposito… - Science …, 2023 - science.org
Macrophages are key cellular contributors to the pathogenesis of COVID-19, the disease
caused by the virus SARS-CoV-2. The SARS-CoV-2 entry receptor ACE2 is present only on …
caused by the virus SARS-CoV-2. The SARS-CoV-2 entry receptor ACE2 is present only on …
CD169-mediated restrictive SARS-CoV-2 infection of macrophages induces pro-inflammatory responses
Exacerbated and persistent innate immune response marked by pro-inflammatory cytokine
expression is thought to be a major driver of chronic COVID-19 pathology. Although …
expression is thought to be a major driver of chronic COVID-19 pathology. Although …
Multipolymer microsphere delivery of SARS-CoV-2 antigens
Effective antigen delivery facilitates antiviral vaccine success defined by effective immune
protective responses against viral exposures. To improve severe acute respiratory syndrome …
protective responses against viral exposures. To improve severe acute respiratory syndrome …
Antiviral peptides against SARS-CoV-2: therapeutic targets, mechanistic antiviral activity, and efficient delivery
The global pandemic of COVID-19 is a serious public health concern. Over 625 million
confirmed cases and more than 6 million deaths have been recorded worldwide. Although …
confirmed cases and more than 6 million deaths have been recorded worldwide. Although …
Europium-doped cerium oxide nanoparticles for microglial amyloid beta clearance and homeostasis
Alzheimer's disease (AD) is the most common neurodegenerative disorder. Pathologically,
the disease is characterized by the deposition of amyloid beta (Aβ) plaques and the …
the disease is characterized by the deposition of amyloid beta (Aβ) plaques and the …
Circulating biomarkers of inflammaging as potential predictors of COVID-19 severe outcomes
J Sabbatinelli, G Matacchione, A Giuliani… - Mechanisms of Ageing …, 2022 - Elsevier
The COVID-19 pandemic caused by SARS-CoV-2 infection has been of unprecedented
clinical and socio-economic worldwide relevance. The case fatality rate for COVID-19 grows …
clinical and socio-economic worldwide relevance. The case fatality rate for COVID-19 grows …
Generation of cytotoxic T cells and dysfunctional CD8 T cells in severe COVID-19 patients
SC Gozzi-Silva, LM Oliveira, RW Alberca, NZ Pereira… - Cells, 2022 - mdpi.com
COVID-19, the infectious disease caused by SARS-CoV-2, has spread on a pandemic scale.
The viral infection can evolve asymptomatically or can generate severe symptoms …
The viral infection can evolve asymptomatically or can generate severe symptoms …
Association of Complement and MAPK Activation With SARS-CoV-2–Associated Myocardial Inflammation
LT Weckbach, L Schweizer, A Kraechan… - JAMA …, 2022 - jamanetwork.com
Importance Myocardial injury is a common feature of patients with SARS-CoV-2 infection.
However, the cardiac inflammatory processes associated with SARS-CoV-2 infection are not …
However, the cardiac inflammatory processes associated with SARS-CoV-2 infection are not …