Recent reports reinforce the notion that nucleosomes are highly dynamic in response to the process of transcription. Nucleosomes are displaced at promoters during gene activation in …
Chromatin structure plays an important role in modulating the accessibility of genomic DNA to regulatory proteins in eukaryotic cells. We performed an integrative analysis on dozens of …
KM Scarpin, JD Graham, PA Mote… - Nuclear receptor …, 2009 - journals.sagepub.com
Progesterone is a critical regulator of normal female reproductive function, with diverse tissue-specific effects in the human. The effects of progesterone are mediated by its nuclear …
K Luger, JC Hansen - Current opinion in structural biology, 2005 - Elsevier
Chromosomal DNA is packaged into condensed nucleoprotein suprastructures, yet the DNA can be accessed as needed within this structural context. Recently, progress has been …
D Angelov, VA Bondarenko, S Almagro… - The EMBO …, 2006 - embopress.org
Remodeling machines play an essential role in the control of gene expression, but how their activity is regulated is not known. Here we report that the nuclear protein nucleolin …
M Buschbeck, I Uribesalgo, I Wibowo, P Rué… - Nature structural & …, 2009 - nature.com
The histone variants macroH2A1 and macroH2A2 are associated with X chromosome inactivation in female mammals. However, the physiological function of macroH2A proteins …
M Ducasse, MA Brown - Molecular cancer, 2006 - Springer
Epigenetic aberrations and cancer | Molecular Cancer Skip to main content SpringerLink Account Menu Find a journal Publish with us Track your research Search Cart 1.Home 2.Molecular …
D Tillo, N Kaplan, IK Moore, Y Fondufe-Mittendorf… - PloS one, 2010 - journals.plos.org
Active eukaryotic regulatory sites are characterized by open chromatin, and yeast promoters and transcription factor binding sites (TFBSs) typically have low intrinsic nucleosome …
The nucleosome, the structural unit of chromatin, is known to play a central role in regulating gene transcription from promoters. The last seven years have spawned a vast amount of …