Glucocorticoids: complications to anticipate and prevent

LS Gensler - The Neurohospitalist, 2013 - journals.sagepub.com
Glucocorticoids (GCs) are widely used for inflammatory and autoimmune diseases. Their
mechanism of action is most commonly rooted in genomic effects that have both beneficial …

Central nervous system effects of natural and synthetic glucocorticoids

P Fietta, P Fietta, G Delsante - Psychiatry and clinical …, 2009 - Wiley Online Library
Natural glucocorticoids (NGC) physiologically modulate body homeostasis and coordinate
adaptive responses to stress, involving almost all organs and tissues, including brain. Since …

Cumulative burden of glucocorticoid-related adverse events in patients with systemic lupus erythematosus: findings from a 12-year longitudinal study

HL Chen, LJ Shen, PN Hsu, CY Shen, SA Hall… - The Journal of …, 2018 - jrheum.org
Objective. The aim of this population-based study is to examine the adverse events (AE)
associated with longitudinal systemic glucocorticoid (GC) use among an ethnic Chinese …

[HTML][HTML] Glucocorticoid therapy and adrenal suppression

NC Nicolaides, AN Pavlaki, M Alexandra, GP Chrousos - 2015 - europepmc.org
Glucocorticoids are steroid hormones produced by the adrenal cortex. They have pleiotropic
effects and contribute substantially to the maintenance of resting and stress-related …

Reproductive outcomes of women with recurrent pregnancy losses and repeated implantation failures are significantly improved with immunomodulatory treatment

N Sung, SA Khan, ME Yiu, G Jubiz, MD Salazar… - Journal of Reproductive …, 2021 - Elsevier
This study investigated if immunomodulatory treatment improves the in-vitro fertilization (IVF)
success rates of women with two or more recurrent pregnancy losses (RPL) and repeated …

Adult-onset Still's disease: pathogenesis, clinical manifestations and therapeutic advances

A Kontzias, P Efthimiou - Drugs, 2008 - Springer
Adult-onset Still's disease (AOSD) is a rare, systemic inflammatory disease of unknown
aetiology, characterized by daily high spiking fevers, evanescent rash and arthritis. Our …

Seven-year tolerability profile of glucocorticoids use in early rheumatoid arthritis: data from the ESPOIR cohort

C Roubille, N Rincheval, M Dougados… - Annals of the …, 2017 - ard.bmj.com
Objective To explore the 7-year tolerability profile of glucocorticoids (GC) for early
rheumatoid arthritis (RA). Methods We examined data for 602 patients with RA from the early …

Glucocorticoids

CM Spies, C Strehl, MC van der Goes… - Best practice & research …, 2011 - Elsevier
Glucocorticoids remain part of the treatment strategy in many rheumatic diseases, because
of their anti-inflammatory and immunosuppressive actions. Unfortunately, their clinically …

Red blood cells for drug delivery

J Yan, J Yu, C Wang, Z Gu - Small Methods, 2017 - Wiley Online Library
Red blood cells (RBCs), or erythrocytes, have been promising endogenous candidates for
drug delivery for more than four decades. Armed with a better understanding of the diverse …

Corticosteroid use in rheumatoid arthritis: prevalence, predictors, correlates, and outcomes.

L Caplan, F Wolfe, AS Russell, K Michaud - The Journal of …, 2007 - jrheum.org
OBJECTIVE: To determine the rate of current and lifetime use of corticosteroids, the degree
of association between corticosteroids and rheumatoid arthritis (RA) activity and outcome …