Intracellular concentrations of redox-active molecules can significantly increase in the heart
as a result of activation of specific signal transduction pathways or the development of …

This study reviews the current understanding of the mechanisms that mediate the complex
processes involved in apoptosis secondary to ischemia and reperfusion (I/R) and is not …

Erythropoietin (EPO) has been shown to protect neurons from ischemic stroke, but can also
increase thrombotic events and mortality rates in patients with ischemic heart disease. We …

Reperfusion injury is an inherent response to the restoration of blood flow after ischemia. It is
a complex process involving numerous mechanisms occurring in the intracellular and …

Ginsenoside Rg1 is a major active ingredient of Panax notoginseng radix which has
demonstrated a number of pharmacological actions including a cardioprotective effect in …

Tanshinones are the major bioactive compounds of Salvia miltiorrhiza Bunge (Danshen)
roots, which are used in many therapeutic remedies in Chinese traditional medicine. We …

Curcumin has been reported to exhibit anti-invasive and/or antimetastatic activities, but the
mechanism remains unclear. In this study, microarray analysis of gene expression profiles …

Glutamine is an essential amino acid in cancer cells and is required for the growth of many
other cell types. Glutaminase activity is positively correlated with malignancy in tumours and …

Carthamus tinctorius L.(safflower) is one of the most commonly used Chinese herbal
medicines to prevent and treat cardiac disease in clinical practice. However, the …

In the present study, we investigated cardioprotective effects of salidroside, isolated from
Rhodiola rosea L, on oxygen–glucose deprivation (OGD)-induced cardiomyocyte death and …