Structural racism in primary schools and changes in epigenetic age acceleration among Black and White youth

CD Martz, AD Benner, BJ Goosby, C Mitchell… - Social Science & …, 2024 - Elsevier
Structural racism generates racial inequities in US primary education, including segregated
schools, inequitable funding and resources, racial disparities in discipline and achievement …

Reduced methylation correlates with diabetic nephropathy risk in type 1 diabetes

I Khurana, H Kaipananickal, S Maxwell… - The Journal of …, 2023 - Am Soc Clin Investig
Diabetic nephropathy (DN) is a polygenic disorder with few risk variants showing robust
replication in large-scale genome-wide association studies. To understand the role of DNA …

Non-coding 886 (nc886/vtRNA2-1), the epigenetic odd duck – implications for future studies

E Raitoharju, S Rajić, S Marttila - Epigenetics, 2024 - Taylor & Francis
ABSTRACT Non-coding 886 (nc886, vtRNA2–1) is the only human polymorphically
imprinted gene, in which the methylation status is not determined by genetics. Existing …

DNA-methylation signatures of tobacco smoking in a high cardiovascular risk population: modulation by the Mediterranean diet

R Fernández-Carrión, JV Sorlí, EM Asensio… - International Journal of …, 2023 - mdpi.com
Biomarkers based on DNA methylation are relevant in the field of environmental health for
precision health. Although tobacco smoking is one of the factors with a strong and consistent …

DNA Methylation in the Anti‐Mullerian Hormone Gene and the Risk of Disease Activity in Multiple Sclerosis

A Giordano, B Pignolet, E Mascia, F Clarelli… - Annals of …, 2024 - Wiley Online Library
Objective Multiple sclerosis (MS) has a complex pathobiology, with genetic and
environmental factors being crucial players. Understanding the mechanisms underlying …

A consistent pattern of slide effects in Illumina DNA methylation BeadChip array data

J Hecker, S Lee, P Kachroo, D Prokopenko… - Epigenetics, 2023 - Taylor & Francis
Background: Recent studies have identified thousands of associations between DNA
methylation CpGs and complex diseases/traits, emphasizing the critical role of epigenetics …

Mother adversity and co-residence time impact mother–child similarity in genome-wide and gene-specific methylation profiles

L Labaut, A Lage-Castellanos, MJ Rodrigo… - Clinical …, 2024 - Springer
Background The effects of adverse life events on physical and psychological health, with
DNA methylation (DNAm) as a critical underlying mechanism, have been extensively …

Associations between the New DNA-Methylation-Based Telomere Length Estimator, the Mediterranean Diet and Genetics in a Spanish Population at High …

O Coltell, EM Asensio, JV Sorlí, C Ortega-Azorín… - Antioxidants, 2023 - mdpi.com
Biological aging is a relevant risk factor for chronic diseases, and several indicators for
measuring this factor have been proposed, with telomere length (TL) among the most …

Simultaneous mapping of epigenetic inter-haplotype, inter-cell and inter-individual variation via the discovery of jointly regulated CpGs in pooled sequencing data

B Planterose Jiménez, B Kolar, M Kayser, A Vidaki - bioRxiv, 2023 - biorxiv.org
In the post-GWAS era, great interest has arisen in the mapping of epigenetic inter-individual
variation towards investigating the emergence of phenotype in health and disease. Relevant …

DNA methylation in T cell leukaemia

M Bensberg - 2024 - diva-portal.org
T cell acute lymphoblastic leukaemia (T-ALL) is a predominantly paediatric cancer that
stems from malignant transformation of developing T cells. While the disease has an overall …