Biomarkers of pathological dissociation: a systematic review

MI Roydeva, AATS Reinders - Neuroscience & Biobehavioral Reviews, 2021 - Elsevier
Pathological dissociation is a severe, debilitating and transdiagnostic psychiatric symptom.
This review identifies biomarkers of pathological dissociation in a transdiagnostic manner to …

From pattern classification to stratification: towards conceptualizing the heterogeneity of Autism Spectrum Disorder

T Wolfers, DL Floris, R Dinga, D van Rooij… - Neuroscience & …, 2019 - Elsevier
Pattern classification and stratification approaches have increasingly been used in research
on Autism Spectrum Disorder (ASD) over the last ten years with the goal of translation …

Individual differences v. the average patient: mapping the heterogeneity in ADHD using normative models

T Wolfers, CF Beckmann, M Hoogman… - Psychological …, 2020 - cambridge.org
BackgroundThe present paper presents a fundamentally novel approach to model individual
differences of persons with the same biologically heterogeneous mental disorder. Unlike …

Uncovering the complex genetics of human character

I Zwir, J Arnedo, C Del-Val, L Pulkki-Råback… - Molecular …, 2020 - nature.com
Abstract Human personality is 30–60% heritable according to twin and adoption studies.
Hundreds of genetic variants are expected to influence its complex development, but few …

Closing the life-cycle of normative modeling using federated hierarchical Bayesian regression

SM Kia, H Huijsdens, S Rutherford, A de Boer, R Dinga… - Plos one, 2022 - journals.plos.org
Clinical neuroimaging data availability has grown substantially in the last decade, providing
the potential for studying heterogeneity in clinical cohorts on a previously unprecedented …

[HTML][HTML] An overview of clustering methods with guidelines for application in mental health research

CX Gao, D Dwyer, Y Zhu, CL Smith, L Du, KM Filia… - Psychiatry …, 2023 - Elsevier
Cluster analyzes have been widely used in mental health research to decompose inter-
individual heterogeneity by identifying more homogeneous subgroups of individuals …

A systematic review and narrative synthesis of data-driven studies in schizophrenia symptoms and cognitive deficits

TD Habtewold, LH Rodijk, EJ Liemburg… - Translational …, 2020 - nature.com
To tackle the phenotypic heterogeneity of schizophrenia, data-driven methods are often
applied to identify subtypes of its symptoms and cognitive deficits. However, a systematic …

Recommendations and future directions for supervised machine learning in psychiatry

M Cearns, T Hahn, BT Baune - Translational psychiatry, 2019 - nature.com
Abstract Machine learning methods hold promise for personalized care in psychiatry,
demonstrating the potential to tailor treatment decisions and stratify patients into clinically …

Beyond the average patient: how neuroimaging models can address heterogeneity in dementia

S Verdi, AF Marquand, JM Schott, JH Cole - Brain, 2021 - academic.oup.com
Dementia is a highly heterogeneous condition, with pronounced individual differences in
age of onset, clinical presentation, progression rates and neuropathological hallmarks, even …

[HTML][HTML] Atypical brain asymmetry in autism—a candidate for clinically meaningful stratification

DL Floris, T Wolfers, M Zabihi, NE Holz… - Biological Psychiatry …, 2021 - Elsevier
Background Autism spectrum disorder (“autism”) is a highly heterogeneous
neurodevelopmental condition with few effective treatments for core and associated …