Current gaps in sepsis immunology: new opportunities for translational research

I Rubio, MF Osuchowski, M Shankar-Hari… - The Lancet infectious …, 2019 - thelancet.com
Increasing evidence supports a central role of the immune system in sepsis, but the current
view of how sepsis affects immunity, and vice versa, is still rudimentary. The European …

Cytokines and fungal infections

C Antachopoulos, E Roilides - British journal of haematology, 2005 - Wiley Online Library
The very poor outcome of invasive fungal infections (IFI) in patients with haematological
malignancies or recipients of haematopoietic stem cell transplantation is largely attributed to …

Melanin of Sporothrix globosa affects the function of THP-1 macrophages and modulates the expression of TLR2 and TLR4

M Guan, L Yao, Y Zhen, Y Song, Y Cui, S Li - Microbial Pathogenesis, 2021 - Elsevier
Background Melanin is an important virulence factor for Sporothrix globosa, the causative
agent of sporotrichosis, a subcutaneous mycosis that occurs worldwide. Although previous …

Pseudomonas aeruginosa in Cancer Therapy: Current Knowledge, Challenges and Future Perspectives

Z Pang, MD Gu, T Tang - Frontiers in Oncology, 2022 - frontiersin.org
Drug resistance, undesirable toxicity and lack of selectivity are the major challenges of
conventional cancer therapies, which cause poor clinical outcomes and high mortality in …

Immune defence mechanisms and immunoenhancement strategies in oropharyngeal candidiasis

CC Villar, A Dongari-Bagtzoglou - Expert reviews in molecular …, 2008 - cambridge.org
The prevalence of oropharyngeal candidiasis continues to be high, mainly because of an
increasing population of immunocompromised patients. Traditional treatment of …

Immunomodulatory activity of protein hydrolysates derived from Virgibacillus halodenitrificans SK1-3-7 proteinase

T Toopcham, JJ Mes, HJ Wichers, J Yongsawatdigul - Food chemistry, 2017 - Elsevier
Modulation of inflammation-related immune response on THP-1 macrophages of protein
hydrolysates derived from tilapia mince, casein and pea protein, were investigated. The …

The Host Immune Response to Scedosporium/Lomentospora

I Buldain, L Martin-Souto, A Antoran, M Areitio… - Journal of Fungi, 2021 - mdpi.com
Infections caused by the opportunistic pathogens Scedosporium/Lomentospora are on the
rise. This causes problems in the clinic due to the difficulty in diagnosing and treating them …

Therapeutic potential of Pseudomonas aeruginosa-mannose sensitive hemagglutinin (PA-MSHA) in cancer treatment

X Zheng, Y Fang, X Zou, X Wang, Z Li - Microbial Pathogenesis, 2023 - Elsevier
Pseudomonas aeruginosa is a Gram-negative bacteria and it has been demonstrated that
immunization with the outer membrane proteins of the microbe produces most of the …

Treatment of Acute Wound Infections by Degradable Polymer Nanoparticle with a Synergistic Photothermal and Chemodynamic Strategy

F Chen, L Liu, D Tang, H Zhang, N Wu… - Advanced …, 2024 - Wiley Online Library
Mild‐heat photothermal antibacterial therapy avoids heat‐induced damage to normal
tissues but causes bacterial tolerance. The use of photothermal therapy in synergy with …

Expression of Cytokine Profiles in Human THP-1 Cells during Phase Transition of Talaromyces marneffei

F Shu, P Thammasit, K Pruksaphon, JD Nosanchuk… - Pathogens, 2022 - mdpi.com
Talaromyces marneffei, a dimorphic fungus, exhibits temperature-dependent growth,
existing in a filamentous form at 25° C and as a yeast at 37° C. Several studies have …