Abstract Purpose of Review We review recent developments on risk factors in
schizophrenia. Recent Findings The way we think about schizophrenia today is profoundly …

Schizophrenia is a heterogeneous psychiatric disorder, which can severely impact social
and professional functioning. Epidemiological and clinical studies show that schizophrenia …

Defining the environmental context in which genes enhance disease susceptibility can
provide insight into the pathogenesis of complex disorders. We report that the intra-uterine …

Background Although the link between cannabis use and development of psychosis is well
established, less is known about the effect of continued versus discontinued cannabis use …

Dopamine is a brain neurotransmitter involved in the pathology of schizophrenia. The
dopamine hypothesis states that, in schizophrenia, dopaminergic signal transduction is …

Genomewide association studies (GWASs) across psychiatric phenotypes have shown that
common genetic variants generally confer risk with small effect sizes (odds ratio< 1.1) that …

Background Although cannabis use after a first episode of psychosis has been associated
with relapse, little is known about the determinants of this most preventable risk factor for …

Schizophrenia and other types of psychosis incur suffering, high health care costs and loss
of human potential, due to the combination of early onset and poor response to treatment …

The underlying cellular mechanisms of catatonia, an executive “psychomotor” syndrome that
is observed across neuropsychiatric diseases, have remained obscure. In humans and …

Genome-wide association studies (GWASs) have identified specific genetic variants
associated with complex human traits and behaviors, such as educational attainment …