In 1665 Robert Hooke, looking at cork through his microscope, discovered that plants are
composed of elementary structures he named “cells”. Variation in the expression of a single …

The past decade has witnessed significant advances in the systemic treatment of advanced
hepatocellular carcinoma (HCC). Nevertheless, the newly developed treatment strategies …

Exploratory spatial data analysis (ESDA) can be a powerful approach to understanding
single-cell genomics datasets, but it is not yet part of standard data analysis workflows. In …

Multimodal, single-cell genomics technologies enable simultaneous capture of multiple
facets of DNA and RNA processing in the cell. This creates opportunities for transcriptome …

Neurodegenerative disorders are typically characterized by late onset progressive damage
to specific (sub) populations of cells of the nervous system that are essential for mobility …

Embryogenesis requires substantial coordination to translate genetic programs to the
collective behavior of differentiating cells, but understanding how cellular decisions control …

To understand how the spinal cord enacts complex sensorimotor functions, researchers
have studied, classified, and functionally probed it's many neuronal populations for over a …

Single-cell RNA sequencing (scRNASeq) data plays a major role in advancing our
understanding of developmental biology. An important current question is how to classify …

In recent years, there have been notable advancements in the ability to programme human
cell identity, enabling us to design and manipulate cell function in a Petri dish. However …

The proliferation of single-cell RNA-seq data has greatly enhanced our ability to
comprehend the intricate nature of diverse tissues. However, accurately annotating cell …