Allometry explores the relationship between an organism's body size and its various
components, offering insights into ecology, physiology, metabolism, and disease. The cell is …

The application of single cell molecular profiling coupled with spatial technologies has
enabled charting cellular heterogeneity in reference tissues and in disease. This new wave …

Animal evolution is influenced by the emergence of new cell types, yet our understanding of
this process remains elusive. This prompts the need for a broader exploration across diverse …

Contribution of the mammalian epiblast to fetal organs during embryogenesis has been
investigated using reporters of marker genes, or through single cell or spatial RNA …

Objectives Single-cell and spatial transcriptomics analysis of human knee articular cartilage
tissue to present a comprehensive transcriptome landscape and osteoarthritis (OA)-critical …

Knowing the ancestral states and lineage relationships of individual cells could unravel the
dynamic programs underlying development. Engineering cells to actively record information …

Comparisons of single-cell RNA sequencing (scRNA-seq) data across species can reveal
links between cellular gene expression and the evolution of cell functions, features, and …

Cell atlas projects curate representative datasets, cell types, and marker genes for tissues
across an organism. Despite their ubiquity, atlas projects rely on duplicated and manual …

Cell type repertoires have expanded extensively in metazoan animals, with some clade-
specific cells being paramount to their evolutionary success. A prime example are the …

The enteric nervous system (ENS) is a tantalizing frontier in neuroscience. With the recent
emergence of single cell transcriptomic technologies, this rare and poorly understood tissue …