With increasing life expectations, more and more patients suffer from fractures either
induced by intensive sports or other bone-related diseases. The balance between …

Osteoporosis, the most common chronic metabolic bone disease, is characterized by low
bone mass and increased bone fragility. Nowadays more than 200 million individuals are …

Systematic bone loss is commonly complicated with inflammatory bowel diseases (IBDs)
with unclear pathogenesis and uncertain treatment. In experimental colitis mouse models …

Background The heterogeneity of mesenchymal stem cells (MSCs) is poorly understood,
thus limiting clinical application and basic research reproducibility. Advanced single‐cell …

Perfluoroalkyl and polyfluoroalkyl substances (PFAS) are a widely dispersed, broad class of
synthetic chemicals with diverse biological effects, including effects on adipose and bone …

Both osteoblasts and preosteoclasts contribute to the coupling of osteogenesis and
angiogenesis, regulating bone regeneration. Astragaloside IV (AS-IV), a glycoside of …

Infertility has been recognized as a civilizational disease. One of the most common causes
of infertility is polycystic ovary syndrome (PCOS). Closely interrelated immunometabolic …

Momordica charantia (M. charantia), commonly known as bitter gourd, bitter melon, kugua,
balsam pear, or karela, is a tropical and sub-tropical vine belonging to the Cucurbitaceae …

Background The imbalance of osteogenic/adipogenic differentiation of bone marrow
mesenchymal stem cells (BMSCs) is closely related to steroid-induced avascular necrosis of …

Although bone is an organ that displays potential for self-healing after damage, bone
regeneration does not occur properly in some cases, and it is still a challenge to treat large …