[HTML][HTML] Structural biology of SARS-CoV-2: open the door for novel therapies

W Yan, Y Zheng, X Zeng, B He, W Cheng - Signal Transduction and …, 2022 - nature.com
Abstract Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2) is the causative
agent of the pandemic disease COVID-19, which is so far without efficacious treatment. The …

[PDF][PDF] Mutasi dan Varian Coronavirus Disease 2019 (COVID-19): Tinjauan Literatur Terkini

A Susilo, COM Jasirwan, S Wafa, S Maria… - Jurnal Penyakit …, 2022 - researchgate.net
ABSTRAK Pandemi Coronavirus disease 2019 (COVID-19) telah berlangsung sejak Maret
2020 hingga saat ini sudah hampir dua tahun melanda dunia, tak terkecuali Indonesia …

Omicron and Delta variant of SARS‐CoV‐2: a comparative computational study of spike protein

S Kumar, TS Thambiraja, K Karuppanan… - Journal of medical …, 2022 - Wiley Online Library
Emerging severe acute respiratory syndrome coronavirus type 2 (SARS‐CoV‐2) variants,
especially those of concern, may have an impact on the virus's transmissibility and …

[PDF][PDF] Structural and functional impact by SARS-CoV-2 Omicron spike mutations

J Zhang, Y Cai, CL Lavine, H Peng, H Zhu, K Anand… - Cell reports, 2022 - cell.com
The Omicron variant of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2),
bearing an unusually high number of mutations, has become a dominant strain in many …

[HTML][HTML] Omicron variant: Current insights and future directions

R Rana, R Kant, RS Huirem, D Bohra… - Microbiological …, 2022 - Elsevier
The global COVID-19 outbreak has returned with the identification of the SARS-CoV-2
Omicron variant (B. 1.1. 529) after appearing to be persistently spreading for the more than …

Conformational dynamics and allosteric modulation of the SARS-CoV-2 spike

MA Díaz-Salinas, Q Li, M Ejemel, L Yurkovetskiy… - Elife, 2022 - elifesciences.org
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infects cells through
binding to angiotensin-converting enzyme 2 (ACE2). This interaction is mediated by the …

[HTML][HTML] Host susceptibility and structural and immunological insight of S proteins of two SARS-CoV-2 closely related bat coronaviruses

X Ou, G Xu, P Li, Y Liu, F Zan, P Liu, J Hu, X Lu… - Cell Discovery, 2023 - nature.com
The bat coronaviruses (CoV) BANAL-20-52 and BANAL-20-236 are two newly identified
severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) closely related …

[HTML][HTML] Machine learning techniques for the prediction of B-cell and T-cell epitopes as potential vaccine targets with a specific focus on SARS-CoV-2 pathogen: A …

SNH Bukhari, A Jain, E Haq, A Mehbodniya, J Webber - Pathogens, 2022 - mdpi.com
The only part of an antigen (a protein molecule found on the surface of a pathogen) that is
composed of epitopes specific to T and B cells is recognized by the human immune system …

A review on structural, non-structural, and accessory proteins of SARS-CoV-2: Highlighting drug target sites

MJ Islam, NN Islam, MS Alom, M Kabir, MA Halim - Immunobiology, 2023 - Elsevier
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the causative agent of
COVID-19, is a highly transmittable and pathogenic human coronavirus that first emerged in …

Protective neutralizing epitopes in SARS‐CoV‐2

H Liu, IA Wilson - Immunological reviews, 2022 - Wiley Online Library
The COVID‐19 pandemic has caused an unprecedented health crisis and economic burden
worldwide. Its etiological agent SARS‐CoV‐2, a new virus in the coronavirus family, has …