The future of the COVID-19 pandemic: How good (or bad) can the SARS-CoV2 spike protein get?

MA Nugent - Cells, 2022 - mdpi.com
Severe acute respiratory syndrome virus 2 (SARS-CoV2) has infected an estimated 400
million people world-wide, causing approximately 6 million deaths from severe coronavirus …

Single-molecule analysis of SARS-CoV-2 binding to c-type lectin receptors

JD Simpson, A Ray, C Marcon… - Nano …, 2023 - ACS Publications
Despite intense scrutiny throughout the pandemic, development of efficacious drugs against
SARS-CoV-2 spread remains hindered. Understanding the underlying mechanisms of viral …

Nanomaterial-Based Biosensors for SARS-CoV-2 and Future Epidemics

P Yari, S Liang, VK Chugh, B Rezaei… - Analytical …, 2023 - ACS Publications
The outbreak of the coronavirus disease 2019 (COVID-19) pandemic has put enormous
pressure on global healthcare and economic systems. 1− 5 The cause of this pandemic …

Design of three residues peptides against SARS-CoV-2 infection

C Zannella, A Chianese, G Greco, B Santella… - Viruses, 2022 - mdpi.com
The continuous and rapid spread of the COVID-19 pandemic has emphasized the need to
seek new therapeutic and prophylactic treatments. Peptide inhibitors are a valid alternative …

Immunogenicity, effectiveness, safety and psychological impact of COVID-19 mRNA vaccines

A Alesci, M Gitto, M Kotańska, PL Cascio, A Miller… - Human Immunology, 2022 - Elsevier
In December 2019, a new single-stranded RNA coronavirus, SARS-CoV-2, appeared in
China and quickly spread around the world leading to a pandemic. Infection with SARS-CoV …

Structure-based drug design of RdRp inhibitors against SARS-CoV-2

K Shehzadi, A Saba, M Yu, J Liang - Topics in Current Chemistry, 2023 - Springer
The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has caused a
worldwide pandemic since 2019, spreading rapidly and posing a significant threat to human …

An immunological review of SARS-CoV-2 infection and vaccine serology: innate and adaptive responses to mRNA, adenovirus, inactivated and protein subunit …

SA Al-Sheboul, B Brown, Y Shboul, I Fricke… - Vaccines, 2022 - mdpi.com
The coronavirus disease 2019 (COVID-19) pandemic is caused by the severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2) virus, which is defined by its positive …

The impact of COVID-19 on cancer patients

D Wekking, TH Senevirathne, JL Pearce… - Cytokine & Growth …, 2023 - Elsevier
The COVID-19 pandemic poses a significant challenge for individuals with compromised
immune systems, such as patients with cancer, as they face a heightened susceptibility to …

Immunogenicity and protective efficacy of SARS-CoV-2 recombinant S-protein vaccine S-268019-b in cynomolgus monkeys

M Hashimoto, N Nagata, T Homma, H Maeda, K Dohi… - Vaccine, 2022 - Elsevier
The vaccine S-268019-b is a severe acute respiratory syndrome coronavirus 2 (SARS-CoV-
2) spike (S)-protein vaccine consisting of full-length recombinant SARS-CoV-2 S-protein (S …

Neutralizing ability of a single domain VNAR antibody: in vitro neutralization of SARS-CoV-2 variants of concern

BJ Valdovino-Navarro, S Dueñas… - International Journal of …, 2022 - mdpi.com
Severe Acute Respiratory Syndrome Coronavirus 2 is the causal pathogen of coronavirus
disease 2019 (COVID-19). The emergence of new variants with different mutational patterns …