Neuroimaging standards for research into small vessel disease—advances since 2013

M Duering, GJ Biessels, A Brodtmann, C Chen… - The Lancet …, 2023 - thelancet.com
Cerebral small vessel disease (SVD) is common during ageing and can present as stroke,
cognitive decline, neurobehavioural symptoms, or functional impairment. SVD frequently …

Cerebral microvascular complications of type 2 diabetes: stroke, cognitive dysfunction, and depression

TT van Sloten, S Sedaghat, MR Carnethon… - The lancet Diabetes & …, 2020 - thelancet.com
Adults with type 2 diabetes are at an increased risk of developing certain brain or mental
disorders, including stroke, dementia, and depression. Although these disorders are not …

Choroid plexus volume and permeability at brain MRI within the Alzheimer disease clinical spectrum

JD Choi, Y Moon, HJ Kim, Y Yim, S Lee, WJ Moon - Radiology, 2022 - pubs.rsna.org
Background Mounting evidence suggests that the choroid plexus (CP) plays an important
role in the pathophysiology of Alzheimer disease (AD), but its imaging profile in cognitive …

The neurovasculome: key roles in brain health and cognitive impairment: a scientific statement from the American Heart Association/American Stroke Association

C Iadecola, EE Smith, J Anrather, C Gu, A Mishra… - Stroke, 2023 - Am Heart Assoc
Background: Preservation of brain health has emerged as a leading public health priority for
the aging world population. Advances in neurovascular biology have revealed an intricate …

Cerebral small vessel disease and vascular cognitive impairment: from diagnosis to management

MCZ Zotin, L Sveikata, A Viswanathan… - Current opinion in …, 2021 - journals.lww.com
SVD is the leading cause of VCI and is associated with substantial morbidity. Tackling
cardiovascular risk factors is currently the most effective approach to prevent cognitive …

Blood–brain barrier link to human cognitive impairment and Alzheimer's disease

G Barisano, A Montagne, K Kisler… - Nature cardiovascular …, 2022 - nature.com
Vascular dysfunction is frequently observed in disorders associated with cognitive
impairment, dementia and Alzheimer's disease (AD). Recent advances in neuroimaging and …

Framework for clinical trials in cerebral small vessel disease (FINESSE): a review

HS Markus, WM van Der Flier, EE Smith, P Bath… - JAMA …, 2022 - jamanetwork.com
Importance Cerebral small vessel disease (SVD) causes a quarter of strokes and is the most
common pathology underlying vascular cognitive impairment and dementia. An important …

Alzheimer's disease: the link between amyloid-β and neurovascular dysfunction

E Solis Jr, KN Hascup… - Journal of Alzheimer's …, 2020 - content.iospress.com
While prevailing evidence supports that the amyloid cascade hypothesis is a key component
of Alzheimer's disease (AD) pathology, many recent studies indicate that the vascular …

Advanced MRI in cerebral small vessel disease

H Van Den Brink, FN Doubal… - International Journal of …, 2023 - journals.sagepub.com
Cerebral small vessel disease (cSVD) is a major cause of stroke and dementia. This review
summarizes recent developments in advanced neuroimaging of cSVD with a focus on …

Cerebral vascular dysfunctions detected in human small vessel disease and implications for preclinical studies

JM Wardlaw, H Benveniste… - Annual Review of …, 2022 - annualreviews.org
Cerebral small vessel disease (SVD) is highly prevalent and a common cause of ischemic
and hemorrhagic stroke and dementia, yet the pathophysiology is poorly understood. Its …