Cellular receptors for viruses: links to tropism and pathogenesis

J Schneider-Schaulies - Journal of General Virology, 2000 - microbiologyresearch.org
The interaction of a virus with its cellular receptor initiates a chain of dynamic events that will
enable entry of the virus into the cell. In addition to the fact that the virus–receptor interaction …

CD46: expanding beyond complement regulation

RC Riley-Vargas, DB Gill, C Kemper, MK Liszewski… - Trends in …, 2004 - cell.com
During the 1980s CD46 was discovered in a search for C3b binding proteins of human
peripheral blood cells. Its role as an inactivator of C3b and C4b deposited on self-tissue is …

Mutations in complement regulatory proteins predispose to preeclampsia: a genetic analysis of the PROMISSE cohort

JE Salmon, C Heuser, M Triebwasser… - PLoS …, 2011 - journals.plos.org
Background Pregnancy in women with systemic lupus erythematosus (SLE) or
antiphospholipid antibodies (APL Ab)—autoimmune conditions characterized by …

Human species D adenovirus hexon capsid protein mediates cell entry through a direct interaction with CD46

BD Persson, L John, K Rafie, M Strebl… - Proceedings of the …, 2021 - National Acad Sciences
Human adenovirus species D (HAdV-D) types are currently being explored as vaccine
vectors for coronavirus disease 2019 (COVID-19) and other severe infectious diseases. The …

[HTML][HTML] Adhesion mechanism of human β2‐glycoprotein I to phospholipids based on its crystal structure

B Bouma, PG de Groot, JMH van den Elsen… - The EMBO …, 1999 - embopress.org
Human β 2‐glycoprotein I is a heavily glycosylated five‐domain plasma membrane‐
adhesion protein, which has been implicated in blood coagulation and clearance of …

[HTML][HTML] Crystal structure of human β2‐glycoprotein I: implications for phospholipid binding and the antiphospholipid syndrome

R Schwarzenbacher, K Zeth, K Diederichs… - The EMBO …, 1999 - embopress.org
The high affinity of human plasma β2‐glycoprotein I (β 2 GPI), also known as apolipoprotein‐
H (ApoH), for negatively charged phospholipids determines its implication in a variety of …

The CD46-Jagged1 interaction is critical for human TH1 immunity

G Le Friec, D Sheppard, P Whiteman, CM Karsten… - Nature …, 2012 - nature.com
CD46 is a complement regulator with important roles related to the immune response. CD46
functions as a pathogen receptor and is a potent costimulator for the induction of interferon-γ …

The human membrane cofactor CD46 is a receptor for species B adenovirus serotype 3

D Sirena, B Lilienfeld, M Eisenhut, S Kälin… - Journal of …, 2004 - Am Soc Microbiol
Many human adenovirus (Ad) serotypes use the coxsackie B virus-Ad receptor (CAR).
Recently, CD46 was suggested to be a receptor of species B Ad serotype 11 (Ad11), Ad14 …

Variola virus immune evasion design: expression of a highly efficient inhibitor of human complement

AM Rosengard, Y Liu, Z Nie… - Proceedings of the …, 2002 - National Acad Sciences
Variola virus, the most virulent member of the genus Orthopoxvirus, specifically infects
humans and has no other animal reservoir. Variola causes the contagious disease …

A Mesh–Duox pathway regulates homeostasis in the insect gut

X Xiao, L Yang, X Pang, R Zhang, Y Zhu, P Wang… - Nature …, 2017 - nature.com
The metazoan gut harbours complex communities of commensal and symbiotic bacterial
microorganisms. The quantity and quality of these microorganisms fluctuate dynamically in …