Intracerebral haemorrhage is inadequately controlled by current treatments, requiring new
solutions to improve the prognosis. Following the primary injury, a proinflammatory cascade …

Acute intracerebral hemorrhage (ICH) is a devastating type of stroke worldwide. Neuronal
destruction involved in the brain damage process caused by ICH includes a primary injury …

Background and Purpose: Neuronal pyroptosis is a type of regulated cell death triggered by
proinflammatory signals. CCR5 (CC chemokine receptor 5)-mediated inflammation is …

Background Owing to metabolic disequilibrium and immune suppression, intracerebral
hemorrhage (ICH) patients are prone to infections; according to a recent global analysis of …

Background Pyroptosis is a programmed cell death mediated by inflammasomes. Previous
studies have reported that inhibition of neurokinin receptor 1 (NK1R) exerted …

Background C–C chemokine receptor type 1 (CCR1) and its endogenous ligand, CCL5,
participate in the pathogenesis of neuroinflammatory diseases. However, much remains …

Intracranial hemorrhage (ICH) is a devastating disease which induces high mortality and
poor outcomes including severe neurological dysfunctions. ICH pathology is divided into two …

Intracerebral hemorrhage (ICH), the most lethal type of stroke, often leads to poor outcomes
in the clinic. Due to the complex mechanisms and cell–cell crosstalk during ICH, the …

Few certainties exist regarding the optimal type, timing, or dosage of rehabilitation after
stroke. Despite differing injury mechanisms and recovery patterns following ischemic and …

Hematoma clearance is an important therapeutic target to improve outcome following
intracerebral hemorrhage (ICH). Recent studies showed that Neurokinin receptor-1 (NK1R) …