[HTML][HTML] A network medicine approach to investigation and population-based validation of disease manifestations and drug repurposing for COVID-19
The global coronavirus disease 2019 (COVID-19) pandemic, caused by severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2), has led to unprecedented social and …
respiratory syndrome coronavirus 2 (SARS-CoV-2), has led to unprecedented social and …
SARS-CoV-2 viral persistence in lung alveolar macrophages is controlled by IFN-γ and NK cells
N Huot, C Planchais, P Rosenbaum, V Contreras… - Nature …, 2023 - nature.com
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) RNA generally becomes
undetectable in upper airways after a few days or weeks postinfection. Here we used a …
undetectable in upper airways after a few days or weeks postinfection. Here we used a …
Two-component spike nanoparticle vaccine protects macaques from SARS-CoV-2 infection
PJM Brouwer, M Brinkkemper, P Maisonnasse… - Cell, 2021 - cell.com
The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic is
continuing to disrupt personal lives, global healthcare systems, and economies. Hence …
continuing to disrupt personal lives, global healthcare systems, and economies. Hence …
Hydroxychloroquine as pre-exposure prophylaxis for coronavirus disease 2019 (COVID-19) in healthcare workers: a randomized trial
R Rajasingham, AS Bangdiwala… - Clinical Infectious …, 2021 - academic.oup.com
Background Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a rapidly
emerging virus causing the ongoing coronavirus disease 2019 (COVID-19) pandemic with …
emerging virus causing the ongoing coronavirus disease 2019 (COVID-19) pandemic with …
Quantifying the relationship between SARS-CoV-2 viral load and infectiousness
The relationship between SARS-CoV-2 viral load and infectiousness is poorly known. Using
data from a cohort of cases and high-risk contacts, we reconstructed viral load at the time of …
data from a cohort of cases and high-risk contacts, we reconstructed viral load at the time of …
Timing of antiviral treatment initiation is critical to reduce SARS‐CoV‐2 viral load
We modeled the viral dynamics of 13 untreated patients infected with severe acute
respiratory syndrome‐coronavirus 2 to infer viral growth parameters and predict the effects …
respiratory syndrome‐coronavirus 2 to infer viral growth parameters and predict the effects …
Comparison of rhesus and cynomolgus macaques as an infection model for COVID-19
FJ Salguero, AD White, GS Slack… - Nature …, 2021 - nature.com
A novel coronavirus, SARS-CoV-2, has been identified as the causative agent of the current
COVID-19 pandemic. Animal models, and in particular non-human primates, are essential to …
COVID-19 pandemic. Animal models, and in particular non-human primates, are essential to …
Azithromycin in viral infections
ME Oliver, TSC Hinks - Reviews in medical virology, 2021 - Wiley Online Library
Azithromycin (AZM) is a synthetic macrolide antibiotic effective against a broad range of
bacterial and mycobacterial infections. Due to an additional range of anti‐viral and anti …
bacterial and mycobacterial infections. Due to an additional range of anti‐viral and anti …
Efficacy and safety of hydroxychloroquine vs placebo for pre-exposure SARS-CoV-2 prophylaxis among health care workers: a randomized clinical trial
BS Abella, EL Jolkovsky, BT Biney… - JAMA internal …, 2021 - jamanetwork.com
Importance Health care workers (HCWs) caring for patients with coronavirus disease 2019
(COVID-19) are at risk of exposure to severe acute respiratory syndrome coronavirus 2 …
(COVID-19) are at risk of exposure to severe acute respiratory syndrome coronavirus 2 …
Low-dose hydroxychloroquine therapy and mortality in hospitalised patients with COVID-19: a nationwide observational study of 8075 participants
Hydroxychloroquine (HCQ) has been largely used and investigated as therapy for COVID-
19 across various settings at a total dose usually ranging from 2400 mg to 9600 mg. In …
19 across various settings at a total dose usually ranging from 2400 mg to 9600 mg. In …