[HTML][HTML] All-cause mortality among patients treated with repurposed antivirals and antibiotics for COVID-19 in Mexico City: A real-world observational study

J Mancilla-Galindo, JÓ García-Méndez… - EXCLI …, 2021 - ncbi.nlm.nih.gov
The aim of our study was to evaluate all-cause mortality risk in patients with laboratory-
confirmed COVID-19 in Mexico City treated with repurposed antivirals and antibiotics. This …

Animal models of COVID-19. I. Comparative virology and disease pathogenesis

CJ Zeiss, S Compton, RT Veenhuis - ILAR journal, 2021 - academic.oup.com
Abstract The Coronavirus Disease 2019 (COVID-19) pandemic has fueled unprecedented
development of animal models to understand disease pathogenesis, test therapeutics, and …

COVID-19 and pregnancy: vertical transmission and inflammation impact on newborns

M Joma, CM Fovet, N Seddiki, P Gressens, M Laforge - Vaccines, 2021 - mdpi.com
The COVID-19 pandemic is ongoing and we are still compiling new findings to decipher and
understand SARS-CoV-2 infection during pregnancy. No reports encompass any conclusive …

Viral modulation of lipid rafts and their potential as putative antiviral targets

YJ Gee, YL Sea, SK Lal - Reviews in Medical Virology, 2023 - Wiley Online Library
Lipid rafts are ubiquitous in cells. They are identified as cholesterol and glycosphingolipid
enriched microdomains on cellular membranes. They serve as platforms for cellular …

[HTML][HTML] Molnupiravir combined with different repurposed drugs further inhibits SARS-CoV-2 infection in human nasal epithelium in vitro

HR Jonsdottir, D Siegrist, T Julien, B Padey… - Biomedicine & …, 2022 - Elsevier
The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has caused a
worldwide pandemic with unprecedented economic and societal impact. Currently, several …

Nanotechnology advances in pathogen-and host-targeted antiviral delivery: multipronged therapeutic intervention for pandemic control

KC Yang, JC Lin, HH Tsai, CY Hsu, V Shih… - Drug Delivery and …, 2021 - Springer
The COVID-19 pandemic's high mortality rate and severe socioeconomic impact serve as a
reminder of the urgent need for effective countermeasures against viral pandemic threats. In …

Could histamine H1 receptor antagonists be used for treating COVID-19?

C Qu, GM Fuhler, Y Pan - International Journal of Molecular Sciences, 2021 - mdpi.com
COVID-19 has rapidly become a pandemic worldwide, causing extensive and long-term
health issues. There is an urgent need to identify therapies that limit SARS-CoV-2 infection …

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) dose, infection, and disease outcomes for coronavirus disease 2019 (COVID-19): a review

LM Brosseau, K Escandón, AK Ulrich… - Clinical Infectious …, 2022 - academic.oup.com
The relationship between severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
dose, infection, and coronavirus disease 2019 (COVID-19) outcomes remains poorly …

Progress and pitfalls of a year of drug repurposing screens against COVID-19

J Sourimant, M Aggarwal, RK Plemper - Current Opinion in Virology, 2021 - Elsevier
Near the end of 2019, a new betacoronavirus started to efficiently transmit between humans,
resulting in the current COVID-19 pandemic. Unprecedented worldwide efforts were made to …

Targeting SARS-CoV-2 receptor-binding domain to cells expressing CD40 improves protection to infection in convalescent macaques

R Marlin, V Godot, S Cardinaud, M Galhaut… - Nature …, 2021 - nature.com
Achieving sufficient worldwide vaccination coverage against SARS-CoV-2 will require
additional approaches to currently approved viral vector and mRNA vaccines. Subunit …