[HTML][HTML] Vitamin D: a role also in long COVID-19?
Coronavirus disease 2019 (COVID-19) has quickly become a global pandemic. Reports
from different parts of the world indicate that a significant proportion of people who have …
from different parts of the world indicate that a significant proportion of people who have …
Sensing of SARS-CoV-2 by pDCs and their subsequent production of IFN-I contribute to macrophage-induced cytokine storm during COVID-19
Lung-infiltrating macrophages create a marked inflammatory milieu in a subset of patients
with COVID-19 by producing a cytokine storm, which correlates with increased lethality …
with COVID-19 by producing a cytokine storm, which correlates with increased lethality …
[HTML][HTML] Factors modulating COVID-19: A mechanistic understanding based on the adverse outcome pathway framework
Addressing factors modulating COVID-19 is crucial since abundant clinical evidence shows
that outcomes are markedly heterogeneous between patients. This requires identifying the …
that outcomes are markedly heterogeneous between patients. This requires identifying the …
[HTML][HTML] Understanding post-COVID-19 interstitial lung disease (ILD): a new fibroinflammatory disease entity
Immunomodulation and immunity from vaccination and natural infection have reduced
mortality from coronavirus disease 2019 (COVID-19). However, there are ongoing concerns …
mortality from coronavirus disease 2019 (COVID-19). However, there are ongoing concerns …
[HTML][HTML] A multicenter, double-blind, randomized, parallel-group, placebo-controlled study to evaluate the efficacy and safety of camostat mesilate in patients with …
T Kinoshita, M Shinoda, Y Nishizaki, K Shiraki, Y Hirai… - BMC medicine, 2022 - Springer
Background In vitro drug screening studies have indicated that camostat mesilate (FOY-305)
may prevent SARS-CoV-2 infection into human airway epithelial cells. This study was …
may prevent SARS-CoV-2 infection into human airway epithelial cells. This study was …
[HTML][HTML] Characterisation of the pro-inflammatory cytokine signature in severe COVID-19
Clinical outcomes from infection with SARS-CoV-2, the cause of the COVID-19 pandemic,
are remarkably variable ranging from asymptomatic infection to severe pneumonia and …
are remarkably variable ranging from asymptomatic infection to severe pneumonia and …
[HTML][HTML] RNA Sequencing in COVID-19 patients identifies neutrophil activation biomarkers as a promising diagnostic platform for infections
R Wargodsky, P Dela Cruz, J LaFleur, D Yamane… - PloS one, 2022 - journals.plos.org
Infection with the SARS-CoV2 virus can vary from asymptomatic, or flu-like with moderate
disease, up to critically severe. Severe disease, termed COVID-19, involves acute …
disease, up to critically severe. Severe disease, termed COVID-19, involves acute …
[HTML][HTML] Clinical and prognostic significance of C-reactive protein to albumin ratio in hospitalized coronavirus disease 2019 (COVID-19) patients: Data on 2309 …
M Lucijanić, J Stojić, A Atić, T Čikara, B Osmani… - Wiener klinische …, 2022 - Springer
C‑reactive protein (CRP) and albumin are inflammation sensitive parameters that are
regulated by interleukin‑6 inflammatory pathways. The CRP to albumin ratio (CAR) …
regulated by interleukin‑6 inflammatory pathways. The CRP to albumin ratio (CAR) …
[HTML][HTML] Autoinflammatory diseases and cytokine storms—imbalances of innate and adaptative immunity
A Marcuzzi, E Melloni, G Zauli, A Romani… - International Journal of …, 2021 - mdpi.com
Innate and adaptive immune responses have a well-known link and represent the distinctive
origins of several diseases, many of which may be the consequence of the loss of balance …
origins of several diseases, many of which may be the consequence of the loss of balance …
[HTML][HTML] Heparin, low molecular weight heparin, and non-anticoagulant derivatives for the treatment of inflammatory lung disease
JK Shute - Pharmaceuticals, 2023 - mdpi.com
Unfractionated heparin has multiple pharmacological activities beyond anticoagulation.
These anti-inflammatory, anti-microbial, and mucoactive activities are shared in part by low …
These anti-inflammatory, anti-microbial, and mucoactive activities are shared in part by low …