NLRP3 Inflammasome's Activation in Acute and Chronic Brain Diseases—An Update on Pathogenetic Mechanisms and Therapeutic Perspectives with Respect to …

A Chiarini, L Gui, C Viviani, U Armato, I Dal Prà - Biomedicines, 2023 - mdpi.com
Increasingly prevalent acute and chronic human brain diseases are scourges for the elderly.
Besides the lack of therapies, these ailments share a neuroinflammation that is …

Are there hidden genes in DNA/RNA vaccines?

CA Beaudoin, M Bartas, A Volná, P Pečinka… - Frontiers in …, 2022 - frontiersin.org
Due to the fast global spreading of the Severe Acute Respiratory Syndrome Coronavirus–2
(SARS-CoV-2), prevention and treatment options are direly needed in order to control …

A peek into Pandora's box: COVID-19 and neurodegeneration

A Chandra, A Johri - Brain Sciences, 2022 - mdpi.com
Ever since it was first reported in Wuhan, China, the coronavirus-induced disease of 2019
(COVID-19) has become an enigma of sorts with ever expanding reports of direct and …

Regulating select agent chimeras: Defining the problem (s) through the lens of SARS-CoV-1/SARS-CoV-2 chimeric viruses

EW Wells, MT Parker - Health security, 2023 - liebertpub.com
In late 2021, the US Centers for Disease Control and Prevention (CDC) posted an interim
final rule (86 FR 64075) to the federal register regulating the possession, use, and transfer of …

Adaptor protein MyD88 confers the susceptibility to stress via amplifying immune danger signals

XP Yao, J Ye, T Feng, FC Jiang, P Zhou, F Wang… - Brain, Behavior, and …, 2023 - Elsevier
Increasing evidence supports the pathogenic role of neuroinflammation in psychiatric
diseases, including major depressive disorder (MDD) and neuropsychiatric symptoms of …

Prenatal SARS-CoV-2 Spike Protein Exposure Induces Autism-Like Neurobehavioral Changes in Male Neonatal Rats

MA Erdogan, M Turk, GD Doganay, IH Sever… - Journal of Neuroimmune …, 2023 - Springer
Recent research on placental, embryo, and brain organoids suggests that the COVID-19
virus may potentially affect embryonic organs, including the brain. Given the established link …

Comprehensive role of SARS‐CoV‐2 spike glycoprotein in regulating host signaling pathway

S Banerjee, X Wang, S Du, C Zhu, Y Jia… - Journal of Medical …, 2022 - Wiley Online Library
Since the outbreak of coronavirus disease 2019 (COVID‐19) caused by severe acute
respiratory syndrome coronavirus 2 (SARS‐CoV‐2) infection, global public health and the …

The Impact of COVID-19 on People Living with HIV-1 and HIV-1-Associated Neurological Complications

D Dutta, J Liu, H Xiong - Viruses, 2023 - mdpi.com
The severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) is the causative
pathogen of the coronavirus disease 2019 (COVID-19) pandemic, a fatal respiratory illness …

[HTML][HTML] Neurological sequela and disruption of neuron-glia homeostasis in SARS-CoV-2 infection

MG Savelieff, EL Feldman, AM Stino - Neurobiology of disease, 2022 - Elsevier
Abstract The coronavirus disease 2019 (COVID-19) pandemic is responsible for 267 million
infections and over 5 million deaths globally. COVID-19 is caused by severe acute …

Nimbolide targets multiple signalling pathways to reduce neuroinflammation in BV-2 microglia

FO Katola, OA Olajide - Molecular Neurobiology, 2023 - Springer
Nimbolide, a limonoid compound found in the neem plant, was investigated for effects on
neuroinflammation in BV-2 microglia activated with lipopolysaccharide (LPS). Cultured BV-2 …