Recent studies show that pre-follicular mouse oogenesis takes place in germline cysts,
highly conserved groups of oogonial cells connected by intercellular bridges that develop as …

Neurodegenerative diseases (NDs), including the most prevalent Alzheimer's disease and
Parkinson disease, share common pathological features. Despite decades of gene‐centric …

Piwi-interacting RNAs are a type of small noncoding RNA that have various functions.
piRBase is a manually curated resource focused on assisting piRNA functional analysis …

Highly potent animal stem cells either self renew or launch complex differentiation programs,
using mechanisms that are only partly understood. Drosophila female germline stem cells …

The major advantage of mRNA vaccines over more conventional approaches is their
potential for rapid development and large-scale deployment in pandemic situations. In the …

Simple Summary Gastrointestinal (GI) cancers are high mortality malignancies due to late
diagnosis, the presence of metastasis and drug resistance development. Novel and more …

Neurodegenerative diseases, such as Alzheimer's disease (AD), Parkinson's disease (PD),
and amyotrophic lateral sclerosis (ALS), are caused by neuronal loss and dysfunction …

Transposable element (TE) mobilization is a constant threat to genome integrity. Eukaryotic
organisms have evolved robust defensive mechanisms to suppress their activity, yet TEs can …

PIWI-interacting small RNAs (piRNAs) protect the germline genome and are essential for
fertility. piRNAs originate from transposable element (TE) RNAs, long non-coding RNAs, or …

Background Understanding genome organization and evolution is important for species
involved in transmission of human diseases, such as mosquitoes. Anophelinae and …