The advent of nanotechnology has reignited interest in the field of pharmaceutical science
for the development of nanomedicine. Nanomedicinal formulations are nanometer-sized …

Delivery of drugs, especially bioactive macromolecules such as proteins and nucleic acids,
to the posterior segment is still a significant challenge for pharmaceutical scientists. In the …

Hesperidin (Hsd), a bioactive phytomedicine, experienced an antidiabetic activity versus
both Type 1 and Type 2 Diabetes mellitus. However, its intrinsic poor solubility and …

Fungal keratitis and endopthalmitis are serious eye diseases. Fluconazole (FL) is indicated
for their treatment, but suffers from poor topical ocular availability. This study was intended to …

Cyclodextrins (CDs) have brought a revolution in the pharmaceutical field over the last
decade. Natural and modified CDs (α-CD and β-CD) have been studied and some have …

The present study was designed to develop dorzolamide HCl (DRZ) loaded cationic
nanoemulsions (CNEs) for enhanced ocular delivery. CNEs were prepared employing high …

This study aimed to develop a cationic nanosuspension of chitosan (CS) and methoxy poly
(ethylene glycol)-poly (ε-caprolactone)(MPEG-PCL) for ocular delivery of diclofenac (DIC) …

Eye diseases, such as dry eye syndrome, are commonly treated with eye drop formulations.
However, eye drop formulations require frequent dosing with high drug concentrations due …

Cyclodextrins (CDs) offer a very broad spectrum of applications in diverse fields of drug
delivery. They are a family of cyclic α-(1–4)-linked oligosaccharides of α-d-glucopyranose …

Melatonin, a neurohormone secreted by the pineal gland, is able to modulate intraocular
pressure (IOP). The aim of this study was to generate nanoparticle (NPs) sustained release …