[HTML][HTML] Insights into SARS-CoV-2 genome, structure, evolution, pathogenesis and therapies: Structural genomics approach

AAT Naqvi, K Fatima, T Mohammad, U Fatima… - … et Biophysica Acta (BBA …, 2020 - Elsevier
The sudden emergence of severe respiratory disease, caused by a novel severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2), has recently become a public health …

SARS-CoV-2 infection: The role of cytokines in COVID-19 disease

VJ Costela-Ruiz, R Illescas-Montes… - Cytokine & growth factor …, 2020 - Elsevier
COVID-19 disease, caused by infection with SARS-CoV-2, is related to a series of
physiopathological mechanisms that mobilize a wide variety of biomolecules, mainly …

The role of cytokines including interleukin-6 in COVID-19 induced pneumonia and macrophage activation syndrome-like disease

D McGonagle, K Sharif, A O'Regan, C Bridgewood - Autoimmunity reviews, 2020 - Elsevier
Severe COVID-19 associated pneumonia patients may exhibit features of systemic hyper-
inflammation designated under the umbrella term of macrophage activation syndrome …

[HTML][HTML] Interplay between SARS-CoV-2 and the type I interferon response

M Sa Ribero, N Jouvenet, M Dreux, S Nisole - PLoS pathogens, 2020 - journals.plos.org
The severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) is responsible for the
current COVID-19 pandemic. An unbalanced immune response, characterized by a weak …

Transcriptomic characteristics of bronchoalveolar lavage fluid and peripheral blood mononuclear cells in COVID-19 patients

Y Xiong, Y Liu, L Cao, D Wang, M Guo… - Emerging microbes & …, 2020 - Taylor & Francis
Circulating in China and 158 other countries and areas, the ongoing COVID-19 outbreak
has caused devastating mortality and posed a great threat to public health. However, efforts …

[HTML][HTML] Associations between immune-suppressive and stimulating drugs and novel COVID-19—a systematic review of current evidence

B Russell, C Moss, G George, A Santaolalla… - …, 2020 - ncbi.nlm.nih.gov
Background Cancer and transplant patients with COVID-19 have a higher risk of developing
severe and even fatal respiratory diseases, especially as they may be treated with immune …

[HTML][HTML] COVID-19 and the immune system

J Paces, Z Strizova, S Daniel, J Cerny - Physiological research, 2020 - ncbi.nlm.nih.gov
A close interaction between the virus SARS-CoV-2 and the immune system of an individual
results in a diverse clinical manifestation of the COVID-19 disease. While adaptive immune …

Nano-curcumin therapy, a promising method in modulating inflammatory cytokines in COVID-19 patients

H Valizadeh, S Abdolmohammadi-Vahid… - International …, 2020 - Elsevier
Background As an ongoing worldwide health issue, Coronavirus disease 2019 (COVID–19)
has been causing serious complications, including pneumonia, acute respiratory distress …

[HTML][HTML] Chest CT features of coronavirus disease 2019 (COVID-19) pneumonia: key points for radiologists

M Carotti, F Salaffi, P Sarzi-Puttini, A Agostini… - La radiologia …, 2020 - Springer
COVID-19 is an emerging infection caused by a novel coronavirus that is moving so rapidly
that on 30 January 2020 the World Health Organization declared the outbreak a Public …

[HTML][HTML] SARS-CoV-2 and COVID-19: Is interleukin-6 (IL-6) the 'culprit lesion'of ARDS onset? What is there besides Tocilizumab? SGP130Fc

G Magro - Cytokine: X, 2020 - Elsevier
Since the outbreak of COVID-19 many studies have been published showing possible
therapies, here the author discusses the end of stage disease related drugs, like …