Integrins are heterodimeric cell surface receptors ensuring the mechanical connection
between cells and the extracellular matrix. In addition to the anchorage of cells to the …

When searching for their favorite host tissues, animal viruses frequently attach to cell-surface
receptors that have key roles in normal cell physiology. Integrins are prime examples of …

We have determined the high resolution crystal structure of the I domain from the α-subunit
of the integrin α2β1, a cell surface adhesion receptor for collagen and the human pathogen …

We previously identified a novel integrin α-chain in human fetal muscle cells (Gullberg, D.,
Velling, T., Sjöberg, G., and Sejersen, T.(1995) Dev. Dyn. 204, 57–65). We have now …

Anthrax toxin is released from Bacillus anthracis as three monomeric proteins, which
assemble into toxic complexes at the surface of receptor-bearing host cells. One of the …

Measles virus is a paramyxovirus which, like other members of the family such as respiratory
syncytial virus, is a major cause of morbidity and mortality worldwide. The cell surface …

Endorepellin, the C-terminal module of perlecan, has angiostatic activity. Here we provide
definitive genetic and biochemical evidence that the functional endorepellin receptor is the …

Parechovirus A is a species in the Parechovirus genus within the Picornaviridae family that
can cause severe disease in children. Relatively little is known on Parechovirus A …

Publisher Summary This chapter discusses the principles governing the integrins, their
capacity to recognize ligands, cellular regulation of integrin function, and aspects of integrin …

Rotavirus NSP4 is a viral enterotoxin capable of causing diarrhea in neonatal mice. This
process is initiated by the binding of extracellular NSP4 to target molecule (s) on the cell …