[HTML][HTML] Long COVID: the nature of thrombotic sequelae determines the necessity of early anticoagulation

C Wang, C Yu, H Jing, X Wu, VA Novakovic… - Frontiers in Cellular …, 2022 - frontiersin.org
Many discharged COVID-19 patients affected by sequelae experience reduced quality of life
leading to an increased burden on the healthcare system, their families and society at large …

[HTML][HTML] Human genetic basis of coronavirus disease 2019

H Deng, X Yan, L Yuan - Signal transduction and targeted therapy, 2021 - nature.com
Abstract Coronavirus disease 2019 (COVID-19) caused by a novel coronavirus, severe
acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has resulted in considerable …

Direct activation of endothelial cells by SARS-CoV-2 nucleocapsid protein is blocked by Simvastatin

Y Qian, T Lei, PS Patel, CH Lee… - Journal of …, 2021 - Am Soc Microbiol
Emerging evidence suggests that endothelial activation plays a central role in the
pathogenesis of acute respiratory distress syndrome (ARDS) and multiorgan failure in …

Caspase-4/11 exacerbates disease severity in SARS–CoV-2 infection by promoting inflammation and immunothrombosis

MM Eltobgy, A Zani, AD Kenney… - Proceedings of the …, 2022 - National Acad Sciences
Severe acute respiratory syndrome coronavirus 2 (SARS–CoV-2) is a worldwide health
concern, and new treatment strategies are needed. Targeting inflammatory innate immunity …

[HTML][HTML] Resveratrol as an adjunctive therapy for excessive oxidative stress in aging COVID-19 patients

MT Liao, CC Wu, SFV Wu, MC Lee, WC Hu, KW Tsai… - Antioxidants, 2021 - mdpi.com
The coronavirus disease 2019 (COVID-19) pandemic continues to burden healthcare
systems worldwide. COVID-19 symptoms are highly heterogeneous, and the patient may be …

[HTML][HTML] Therapeutic effects of inhaled nitric oxide therapy in COVID-19 patients

NO Kamenshchikov, L Berra, RW Carroll - Biomedicines, 2022 - mdpi.com
The global COVID-19 pandemic has become the largest public health challenge of recent
years. The incidence of COVID-19-related acute hypoxemic respiratory failure (AHRF) …

[HTML][HTML] Endothelial cell activation by SARS-CoV-2 spike S1 protein: a crosstalk between endothelium and innate immune cells

BM Rotoli, A Barilli, R Visigalli, F Ferrari, V Dall'Asta - Biomedicines, 2021 - mdpi.com
Background. Emerging evidences suggest that in severe COVID-19, multi-organ failure is
associated with a hyperinflammatory state (the so-called “cytokine storm”) in combination …

[HTML][HTML] Among classic myeloproliferative neoplasms, essential thrombocythemia is associated with the greatest risk of venous thromboembolism during COVID-19

T Barbui, V De Stefano, A Alvarez-Larran, A Iurlo… - Blood cancer …, 2021 - nature.com
In a multicenter European retrospective study including 162 patients with COVID-19
occurring in essential thrombocythemia (ET, n= 48), polycythemia vera (PV, n= 42) …

[HTML][HTML] The right ventricle in COVID-19

J Bonnemain, Z Ltaief, L Liaudet - Journal of clinical medicine, 2021 - mdpi.com
Infection with the novel severe acute respiratory coronavirus-2 (SARS-CoV2) results in
COVID-19, a disease primarily affecting the respiratory system to provoke a spectrum of …

[HTML][HTML] COVID-19-induced gastrointestinal autonomic dysfunction: A systematic review

R Elbeltagi, M Al-Beltagi, NK Saeed… - World Journal of …, 2023 - ncbi.nlm.nih.gov
BACKGROUND It is common for severe acute respiratory syndrome coronavirus 2 (SARS-
CoV-2) infection to occur in the gastrointestinal tract, which can present itself as an initial …