[HTML][HTML] A detailed overview of immune escape, antibody escape, partial vaccine escape of SARS-CoV-2 and their emerging variants with escape mutations

C Chakraborty, AR Sharma, M Bhattacharya… - Frontiers in …, 2022 - frontiersin.org
The infective SARS-CoV-2 is more prone to immune escape. Presently, the significant
variants of SARS-CoV-2 are emerging in due course of time with substantial mutations …

[HTML][HTML] Integrative overview of antibodies against SARS-CoV-2 and their possible applications in COVID-19 prophylaxis and treatment

NA Valdez-Cruz, E García-Hernández, C Espitia… - Microbial cell …, 2021 - Springer
SARS-CoV-2 is a novel β-coronavirus that caused the COVID-19 pandemic disease, which
spread rapidly, infecting more than 134 million people, and killing almost 2.9 million thus far …

[HTML][HTML] SARS-CoV-2 escape in vitro from a highly neutralizing COVID-19 convalescent plasma

E Andreano, G Piccini, D Licastro, L Casalino… - BioRxiv, 2020 - ncbi.nlm.nih.gov
To investigate the evolution of SARS-CoV-2 in the immune population, we co-incubated
authentic virus with a highly neutralizing plasma from a COVID-19 convalescent patient. The …

SARS-CoV-2 escape from a highly neutralizing COVID-19 convalescent plasma

E Andreano, G Piccini, D Licastro… - Proceedings of the …, 2021 - National Acad Sciences
To investigate the evolution of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-
2) in the immune population, we coincupi bated the authentic virus with a highly neutralizing …

[HTML][HTML] A variant-proof SARS-CoV-2 vaccine targeting HR1 domain in S2 subunit of spike protein

W Pang, Y Lu, YB Zhao, F Shen, CF Fan, Q Wang… - Cell Research, 2022 - nature.com
The emerging SARS-CoV-2 variants, commonly with many mutations in S1 subunit of spike
(S) protein are weakening the efficacy of the current vaccines and antibody therapeutics …

[PDF][PDF] Isolation and characterization of cross-neutralizing coronavirus antibodies from COVID-19+ subjects

MF Jennewein, AJ MacCamy, NR Akins, J Feng… - Cell reports, 2021 - cell.com
SARS-CoV-2 is one of three coronaviruses that have crossed the animal-to-human barrier
and caused widespread disease in the past two decades. The development of a universal …

[HTML][HTML] The binding of heparin to spike glycoprotein inhibits SARS-CoV-2 infection by three mechanisms

G Paiardi, S Richter, P Oreste, C Urbinati… - Journal of Biological …, 2022 - ASBMB
Heparin, a naturally occurring glycosaminoglycan, has been found to have antiviral activity
against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the causative virus …

[PDF][PDF] A neutralizing epitope on the SD1 domain of SARS-CoV-2 spike targeted following infection and vaccination

J Seow, H Khan, A Rosa, V Calvaresi, C Graham… - Cell Reports, 2022 - cell.com
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike is the target for
neutralizing antibodies elicited following both infection and vaccination. While extensive …

Conformational dynamics and allosteric modulation of the SARS-CoV-2 spike

MA Díaz-Salinas, Q Li, M Ejemel, L Yurkovetskiy… - Elife, 2022 - elifesciences.org
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infects cells through
binding to angiotensin-converting enzyme 2 (ACE2). This interaction is mediated by the …

[HTML][HTML] Monoclonal antibodies for COVID-19 therapy and SARS-CoV-2 detection

YC Hwang, RM Lu, SC Su, PY Chiang, SH Ko… - Journal of Biomedical …, 2022 - Springer
Abstract The coronavirus disease 2019 (COVID-19) pandemic is an exceptional public
health crisis that demands the timely creation of new therapeutics and viral detection. Owing …