Systematic reviews seek to identify all research that meets the eligibility criteria. However,
this goal can be compromised by 'non‐reporting bias'. The convincing evidence for the …

Registered Reports are a form of empirical publication in which study proposals are peer
reviewed and pre-accepted before research is undertaken. By deciding which articles are …

Background Failure to report the results of a clinical trial can distort the evidence base for
clinical practice, breaches researchers' ethical obligations to participants, and represents an …

Background Dickersin and Min define publication bias as the failure to publish the results of
a study 'on the basis of the direction or strength of the study findings'. 1 This non-publication …

The success of protein engineering and design has extensively expanded the protein space,
which presents a promising strategy for creating next-generation proteins of diverse …

Big data, coupled with the use of advanced analytical approaches, such as artificial
intelligence (AI), have the potential to improve medical outcomes and population health …

In recent years there has been increasing awareness of problems that have undermined
trust in medical research. This review outlines some of the most important issues including …

To gain insight into changes of scholarly journals' recommendations, we conducted a
systematic review of studies that analysed journals' Instructions to Authors (ItAs). We …

Summary The Human Pluripotent Stem Cell Registry established a database of clinical
studies using human pluripotent stem cells (PSCs) as starting material for cell therapies …

Power analysis currently dominates sample size determination for experiments, particularly
in grant and ethics applications. Yet, this focus could paradoxically result in suboptimal study …