The role of serotonin 5-HT2A receptors in memory and cognition
G Zhang, RW Stackman Jr - Frontiers in pharmacology, 2015 - frontiersin.org
Serotonin 5-HT2A receptors (5-HT2ARs) are widely distributed in the central nervous
system, especially in brain region essential for learning and cognition. In addition to …
system, especially in brain region essential for learning and cognition. In addition to …
Structural insights into the lipid and ligand regulation of serotonin receptors
Abstract Serotonin, or 5-hydroxytryptamine (5-HT), is an important neurotransmitter, that
activates the largest subtype family of G-protein-coupled receptors. Drugs that target 5 …
activates the largest subtype family of G-protein-coupled receptors. Drugs that target 5 …
Structural basis of ligand recognition at the human MT1 melatonin receptor
Abstract Melatonin (N-acetyl-5-methoxytryptamine) is a neurohormone that maintains
circadian rhythms by synchronization to environmental cues and is involved in diverse …
circadian rhythms by synchronization to environmental cues and is involved in diverse …
Modulating the neuromodulators: dopamine, serotonin, and the endocannabinoid system
Dopamine (DA), serotonin (5-hydroxytryptamine, 5-HT), and endocannabinoids (ECs) are
key neuromodulators involved in many aspects of motivated behavior, including reward …
key neuromodulators involved in many aspects of motivated behavior, including reward …
Subcortical serotonin 5HT2c receptor-containing neurons sex-specifically regulate binge-like alcohol consumption, social, and arousal behaviors in mice
ME Flanigan, OJ Hon, S D'Ambrosio, KM Boyt… - Nature …, 2023 - nature.com
Binge alcohol consumption induces discrete social and arousal disturbances in human
populations that promote increased drinking and accelerate the progression of Alcohol Use …
populations that promote increased drinking and accelerate the progression of Alcohol Use …
Serotonin 5-HT2 receptor interactions with dopamine function: implications for therapeutics in cocaine use disorder
LL Howell, KA Cunningham - Pharmacological reviews, 2015 - ASPET
Cocaine exhibits prominent abuse liability, and chronic abuse can result in cocaine use
disorder with significant morbidity. Major advances have been made in delineating …
disorder with significant morbidity. Major advances have been made in delineating …
The implication of 5-HT receptor family members in aggression, depression and suicide: similarity and difference
NK Popova, AS Tsybko, VS Naumenko - International journal of molecular …, 2022 - mdpi.com
Being different multifactorial forms of psychopathology, aggression, depression and suicidal
behavior, which is considered to be violent aggression directed against the self, have …
behavior, which is considered to be violent aggression directed against the self, have …
The role of serotonin receptor subtypes in treating depression: a review of animal studies
GV Carr, I Lucki - Psychopharmacology, 2011 - Springer
Abstract Rationale Serotonin reuptake inhibitors (SSRIs) are effective in treating depression.
Given the existence of different families and subtypes of 5-HT receptors, multiple 5-HT …
Given the existence of different families and subtypes of 5-HT receptors, multiple 5-HT …
Rapid modulation of spine morphology by the 5-HT2A serotonin receptor through kalirin-7 signaling
The 5-HT2A serotonin receptor is the most abundant serotonin receptor subtype in the
cortex and is predominantly expressed in pyramidal neurons. The 5-HT2A receptor is a …
cortex and is predominantly expressed in pyramidal neurons. The 5-HT2A receptor is a …