It has been known that a considerable number of drugs in clinical use or under development
are water-insoluble drugs with poor bioavailability (BA). The liposomal delivery system has …

Diet can be considered as one of the pivotal factors in regulating gastrointestinal health, and
polyphenols widely distributed in human daily diet. The polyphenols and their metabolites …

Hesperidin and hesperetin are polyphenols that can be found predominantly in citrus fruits.
They possess a variety of pharmacological properties such as neuroprotective and …

COVID-19 pandemic has spread worldwide at an exponential rate affecting millions of
people instantaneously. Currently, various drugs are under investigation to treat an …

Recent pandemic situation of COVID-19 is caused due to SARS-CoV2 and almost all the
countries of the world have been affected by this highly contagious virus. Main protease (M …

There are significant differences between men and women in the efficacy and tolerability of
antipsychotic drugs. Here, we provide a comprehensive overview of what is currently known …

Aim: We aimed to systematically evaluate the prevalence and clinical characteristics of
adverse events associated with the adaptogens and antidepressant drug interactions in a …

The effect of membrane transporters on drug disposition, efficacy and safety is now well
recognized. Since the initial publication from the International Transporter Consortium …

Abstract Context Bupleuri Radix, the dried root of Bupleurum chinense DC and Bupleurum
scorzonerifolium Willd (Apiaceae), is an important medicinal herb widely used to treat …

Pharmacokinetic drug–drug interactions (DDIs) occur when a drug alters the absorption,
transport, distribution, metabolism or excretion of a co-administered agent. The occurrence …