[HTML][HTML] Effects of DNA, RNA, and Protein Methylation on the Regulation of Ferroptosis

X Wang, X Kong, X Feng, DS Jiang - International Journal of …, 2023 - ncbi.nlm.nih.gov
Ferroptosis is a form of programmed cell death characterized by elevated intracellular
ferrous ion levels and increased lipid peroxidation. Since its discovery and characterization …

The mechanism of ferroptosis and its related diseases

S Feng, D Tang, Y Wang, X Li, H Bao, C Tang… - Molecular …, 2023 - Springer
Ferroptosis, a regulated form of cellular death characterized by the iron-mediated
accumulation of lipid peroxides, provides a novel avenue for delving into the intersection of …

METTL3‐mediated N6‐methyladenosine exacerbates ferroptosis via m6A‐IGF2BP2‐dependent mitochondrial metabolic reprogramming in sepsis‐induced acute lung …

H Zhang, D Wu, Y Wang, K Guo… - Clinical and …, 2023 - Wiley Online Library
Neutrophil extracellular traps (NETs), released by polymorphonuclear neutrophils (PMNs),
exert a robust antimicrobial function in infectious diseases such as sepsis. NETs also …

[HTML][HTML] FTO ameliorates doxorubicin-induced cardiotoxicity by inhibiting ferroptosis via P53–P21/Nrf2 activation in a HuR-dependent m6A manner

Y Yang, J Ren, J Zhang, H Shi, J Wang, Y Yan - Redox Biology, 2024 - Elsevier
Doxorubicin (DOX)-induced cardiotoxicity seriously limits its clinical applicability, and no
therapeutic interventions are available. Ferroptosis, an iron-dependent regulated cell death …

RNA m6A methylation regulators in sepsis

L Zhu, H Zhang, X Zhang, L Xia - Molecular and Cellular Biochemistry, 2023 - Springer
Abstract N6-methyladenosine (m6A) modification is a class of epitope modifications that has
received significant attention in recent years, particularly in relation to its role in various …

[HTML][HTML] Insights into the role of N6-methyladenosine in ferroptosis

J Zhang, T Qiu, X Yao, X Sun - Biomedicine & Pharmacotherapy, 2023 - Elsevier
Abstract N6-methyladenosine (m 6 A) methylation modification is one of the most prevalent
epigenetic modifications of eukaryotic RNA. m 6 A methylation is widely associated with …

Current insight on the mechanisms of programmed cell death in sepsis-induced myocardial dysfunction

AB Liu, SJ Li, YY Yu, JF Zhang, L Ma - Frontiers in Cell and …, 2023 - frontiersin.org
Sepsis is a clinical syndrome characterized by a dysregulated host response to infection,
leading to life-threatening organ dysfunction. It is a high-fatality condition associated with a …

N6-methyladenosine (m6A) reader YTHDF2 accelerates endothelial cells ferroptosis in cerebrovascular atherosclerosis

J Li, C Zou, Z Zhang, F Xue - Molecular and Cellular Biochemistry, 2023 - Springer
Cerebrovascular diseases have extreme high mortality and disability rate worldwide, and
endothelial cells injury-induced atherosclerosis acts as the main cause of cerebrovascular …

RNA methylation reading protein YTHDF2 relieves myocardial ischemia–reperfusion injury by downregulating BNIP3 via m6A modification

X Cai, P Zou, L Hong, Y Chen, Y Zhan, Y Liu, L Shao - Human Cell, 2023 - Springer
BNIP3 is reported to be involved in hypoxia-induced mitochondrial defect and cell death in
cardiomyocytes. However, little is known about the specific function and molecular …

Changes of RNA m6A/m5C Modification Regulatory Molecules in Ferroptosis of T2DM Rat Pancreas

X Liu, N Wang, S Gu, Z He - Cell Biochemistry and Biophysics, 2024 - Springer
Abstract N6-methyladenine (m6A) and 5-methylcytosine (m5C) are two common forms of
RNA methylation that play an important role in the epigenetics of type 2 diabetes mellitus …