Icariin is a biologically active substance in Epimedii herba that is used for the treatment of
neurologic disorders. However, a comprehensive analysis of the molecular mechanisms of …

Arsenic is a widely existing pollutant in the environment, but the mechanism of occurrence
and development of lung cancer by long-term arsenic exposure needs to be elucidated …

Colorectal cancer is a highly prevalent cancer with a high mortality rate. Although the
colorectal carcinogenesis mechanism is not fully understood yet, it has been proven that …

A‐kinase anchoring protein 95 (AKAP95) functions as a scaffold for protein kinase A. Prior
work by our group has shown that AKAP95, in coordination with Connexin 43 (Cx43) …

Purpose: Cx43 (connexin 43) has been found to inhibit cell cycle of tumor cells. No nuclear
localization sequence of Cx43 was found but the protein has been found in nucleus. The …

Background: Arsenide, a kind of pollution widely existing in the environment, and the
mechanism of occurrence and development of lung cancer leading by long-term arsenic …

Background AKAP95 (A-kinase anchoring protein) and Cx43 (connexin 43) express
abnormally in lung cancer cells. As potential tumor therapeutic targets, specific process of …