Promising antiviral activities of natural flavonoids against SARS-CoV-2 targets: systematic review

R Kaul, P Paul, S Kumar, D Büsselberg… - International journal of …, 2021 - mdpi.com
The ongoing COVID-19 pandemic, caused by the severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2) became a globally leading public health concern over the past …

The main protease of SARS-CoV-2 as a target for phytochemicals against coronavirus

SS Issa, SV Sokornova, RR Zhidkin, TV Matveeva - Plants, 2022 - mdpi.com
In late December 2019, the first cases of COVID-19 emerged as an outbreak in Wuhan,
China that later spread vastly around the world, evolving into a pandemic and one of the …

Synthesis, Crystal Structure, DFT Calculations, Hirshfeld Surface Analysis and In Silico Drug-Target Profiling of (R)-2-(2-(1,3-Dioxoisoindolin-2-yl)propanamido) …

SL Rubab, AR Raza, B Nisar, M Ashfaq, Y Altaf… - Molecules, 2023 - mdpi.com
The work here reflects synthesis, DFT studies, Hirshfeld charge analysis and crystal data
exploration of pharmacologically important (R)-2-(2-(1, 3-dioxoisoindolin-2-yl) propanamido) …

Food spoilage and Microorganisms

M Sevindik, I Uysal - … Journal of Agriculture-Food Science and …, 2021 - agrifoodscience.com
Food spoilage is an undesirable process and is a serious problem for humans. There are
many factors that accelerate and affect food spoilage. In this study, microbial behaviors in …

Molecular docking and dynamics investigations for identifying potential inhibitors of the 3-chymotrypsin-like protease of SARS-CoV-2: repurposing of approved …

AO Elzupir - Molecules, 2021 - mdpi.com
This study demonstrates the inhibitory effect of 42 pyrimidonic pharmaceuticals (PPs) on the
3-chymotrypsin-like protease of SARS-CoV-2 (3CLpro) through molecular docking …

In Silico and In Vitro Studies of 4-Hydroxycoumarin-Based Heterocyclic Enamines as Potential Anti-Tumor Agents

M Assad, RN Paracha, AB Siddique, MA Shaheen… - Molecules, 2023 - mdpi.com
The present study reports the one-step synthesis of several 3-formyl-4-hydroxycouramin-
derived enamines (4a–4i) in good yields (65–94%). The characterization of the synthesized …

Ficus benghalensis as Potential Inhibitor of 5α-Reductase for Hair Growth Promotion: In Vitro, In Silico, and In Vivo Evaluation

J Iltaf, S Noreen, MFU Rehman… - Frontiers in …, 2021 - frontiersin.org
The screening of hair follicles, dermal papilla cells, and keratinocytes through in vitro, in
vivo, and histology has previously been reported to combat alopecia. Ficus benghalensis …

Pharmacoinformatic study of inhibitory potentials of selected flavonoids against papain-like protease and 3-chymotrypsin-like protease of SARS-CoV-2

H Tijjani, AP Adegunloye, A Uba, JO Adebayo… - Clinical …, 2022 - Springer
Background Inhibition of papain-like protease (PLpro) and 3-chymotrypsin-like protease
(3CLpro) of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is projected to …

Natural compounds from medicinal plants against COVID-19

A Kolodnitsky, N Ionov, I Gravel… - Exploration of Drug …, 2023 - explorationpub.com
The severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2), known to cause the
coronavirus disease 2019 (COVID-19), was declared a pandemic in early 2020. During the …

Bioavailability enhancement of cepharanthine via pulmonary administration in rats and its therapeutic potential for pulmonary fibrosis associated with COVID-19 …

J Li, G Chen, Z Meng, Z Wu, H Gan, X Zhu, P Han, T Liu… - Molecules, 2022 - mdpi.com
Cepharanthine (CEP) has excellent anti-SARS-CoV-2 properties, indicating its favorable
potential for COVID-19 treatment. However, its application is challenged by its poor …