Coagulation abnormalities and thrombosis in patients infected with SARS-CoV-2 and other pandemic viruses
N Mackman, S Antoniak, AS Wolberg… - … , and vascular biology, 2020 - Am Heart Assoc
The world is amid a pandemic caused by severe acute respiratory syndrome-coronavirus 2.
Severe acute respiratory syndrome-coronavirus causes serious respiratory tract infections …
Severe acute respiratory syndrome-coronavirus causes serious respiratory tract infections …
[HTML][HTML] Severe COVID-19 and aging: are monocytes the key?
BD Pence - Geroscience, 2020 - Springer
The ongoing pandemic severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2)
causes a disproportionate number of severe cases and deaths in older adults. Severe SARS …
causes a disproportionate number of severe cases and deaths in older adults. Severe SARS …
Cytokine release syndrome in severe COVID-19: interleukin-6 receptor antagonist tocilizumab may be the key to reduce mortality
C Zhang, Z Wu, JW Li, H Zhao, GQ Wang - International journal of …, 2020 - Elsevier
Since December 2019, a viral pneumonia, named coronavirus disease 2019 (COVID-19),
from Wuhan, China, has swept the world. Although the case fatality rate is not high, the …
from Wuhan, China, has swept the world. Although the case fatality rate is not high, the …
[HTML][HTML] Cytokine profiles associated with acute COVID-19 and long COVID-19 syndrome
MAF Queiroz, PFM Neves, SS Lima… - Frontiers in cellular …, 2022 - frontiersin.org
The duration and severity of COVID-19 are related to age, comorbidities, and cytokine
synthesis. This study evaluated the impact of these factors on patients with clinical …
synthesis. This study evaluated the impact of these factors on patients with clinical …
[HTML][HTML] Tocilizumab among patients with COVID-19 in the intensive care unit: a multicentre observational study
Background Tocilizumab, a monoclonal antibody directed against the interleukin-6 receptor,
has been proposed to mitigate the cytokine storm syndrome associated with severe COVID …
has been proposed to mitigate the cytokine storm syndrome associated with severe COVID …
Cloaking mesoporous polydopamine with bacterial membrane vesicles to amplify local and systemic antitumor immunity
W Chen, Y Song, S Bai, C He, Z Guo, Y Zhu, Z Zhang… - ACS …, 2023 - ACS Publications
As adjuvants or antigens, bacterial membranes have been widely used in recent
antibacterial and antitumor research, but they are often injected multiple times to achieve …
antibacterial and antitumor research, but they are often injected multiple times to achieve …
Host-directed antiviral therapy
Antiviral drugs have traditionally been developed by directly targeting essential viral
components. However, this strategy often fails due to the rapid generation of drug-resistant …
components. However, this strategy often fails due to the rapid generation of drug-resistant …
The looming storm: blood and cytokines in COVID-19
A novel coronavirus termed as COVID-19 by WHO has been the causative agent of an
unprecedented pandemic in the history of humanity. The global burden of mortality and …
unprecedented pandemic in the history of humanity. The global burden of mortality and …
[HTML][HTML] The role of IL-6 in coronavirus, especially in COVID-19
X Wang, G Tang, Y Liu, L Zhang, B Chen… - Frontiers in …, 2022 - frontiersin.org
Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) infects both people and
animals and may cause significant respiratory problems, including lung illness: Corona …
animals and may cause significant respiratory problems, including lung illness: Corona …
[HTML][HTML] Epigenetic signatures underlying inflammation: An interplay of nutrition, physical activity, metabolic diseases, and environmental factors for personalized …
Aim and objective Emerging translational evidence suggests that epigenetic alterations
(DNA methylation, miRNA expression, and histone modifications) occur after external stimuli …
(DNA methylation, miRNA expression, and histone modifications) occur after external stimuli …