Lymphatic endothelial cells under mechanical stress: altered expression of inflammatory cytokines and fibrosis

S Wang, D Nie, JP Rubin, L Kokai - Lymphatic research and biology, 2017 - liebertpub.com
Background: Secondary lymphedema, resulting from damage to lymphatic vessels, is a
common sequela following surgical removal of lymph nodes for cancer. Current therapeutics …

Lymphatic vessel function in head and neck inflammation

LA Truman, N A-Gonzalez, KL Bentley… - … research and biology, 2013 - liebertpub.com
Background: Serious infections of the head and neck cause lymphedema that can lead to
airway compromise and oropharyngeal obstruction. Lymphangiogenesis occurs in the head …

New imaging methods and tools to study vascular biology

B Lavina, K Gaengel - Current opinion in hematology, 2015 - journals.lww.com
Major recent improvements in a number of imaging techniques now allow study of vascular
biology in ways that could not be considered previously. Researchers now have well …

CD8 T Cell Memory Inflation is Driven by Latent CMV Infection of Lymphatic Endothelial Cells

MW Munks, K Rott, PA Nesterenko, SM Smart… - bioRxiv, 2022 - biorxiv.org
ABSTRACT CMV, a ubiquitous herpesvirus, elicits an extraordinarily large T cell response
that is sustained or increases over time, a phenomenon termed 'memory …

[HTML][HTML] Lymphatic vessels enhancing adaptive immunity deteriorates renal inflammation and renal fibrosis

J Wu, G Pei, R Zeng, G Xu - Kidney Diseases, 2020 - karger.com
Background: Lymphatic vessels transport lymph away from microvascular beds into the
cardiovascular system. The basic function of the lymphatic system include absorption of …

Aging induces Nlrp3 inflammasome dependent adipose B cell expansion to impair metabolic homeostasis

CD Camell, A Lee, P Günther, EL Goldberg, O Spadaro… - bioRxiv, 2019 - biorxiv.org
Visceral adiposity in elderly is associated with alterations in adipose tissue immune cells
leading to inflammation and metabolic dysfunction. The Nlrp3 inflammasome is a critical …

[图书][B] Targeting N-acetyl-L-aspartate synthesis and transport for treatment of Canavan leukodystrophy

VL Hull - 2023 - search.proquest.com
Canavan disease (CD) is an incurable, progressive leukodystrophy that develops in infancy
as the result of Aspa mutations which disrupt the functionality of aspartoacylase (ASPA) …

Lymphatic drainage system and lymphatic metastasis of cancer cells in the mouse esophagus

Y Li, Q Cheng, Z Xiong, C Paiboonrungruang… - Digestive diseases and …, 2023 - Springer
Background Lymphatic metastasis is commonly seen in patients with esophageal squamous
cell carcinoma (ESCC). Both lymphatic metastasis and the number of involved nodes are …

Bronchus-associated macrophages are positioned for soluble antigen capture from the airway lumen and for local Th2 cell activation

XZ Tang, LSM Kreuk, C Cho, RJ Metzger, CDC Allen - bioRxiv, 2020 - biorxiv.org
The aberrant activation of immune responses at barrier surfaces may lead to pathological
inflammation. In allergic asthma, allergen inhalation leads to peri-bronchial inflammation …

Kidney lymphatics

PS Russell, M Itkin, JA Windsor… - Comprehensive …, 2011 - Wiley Online Library
Following significant advances in lymphatic biology, the important role of kidney lymphatics
in kidney function and dysfunction is now being more fully appreciated. Kidney lymphatics …