The role of testosterone, the androgen receptor, and hypothalamic-pituitary–gonadal axis in depression in ageing Men

RL Hauger, UG Saelzler, MS Pagadala… - Reviews in Endocrine …, 2022 - Springer
Considerable research has shown that testosterone regulates many physiological systems,
modulates clinical disorders, and contributes to health outcome. However, studies on the …

Anabolic androgenic steroids and cardiomyopathy: an update

K Fadah, G Gopi, A Lingireddy, V Blumer… - Frontiers in …, 2023 - frontiersin.org
Anabolic androgenic steroids (AAS) include endogenously produced androgens like
testosterone and their synthetic derivatives. Their influence on multiple metabolic pathways …

[HTML][HTML] Effects of long-term testosterone treatment on cardiovascular outcomes in men with hypogonadism: rationale and design of the TRAVERSE study

S Bhasin, AM Lincoff, S Basaria, DC Bauer… - American Heart …, 2022 - Elsevier
Background Testosterone exerts some effects on the cardiovascular system that could be
considered beneficial; some other effects may potentially increase the risk of cardiovascular …

The treatment of chronic anemia in heart failure: a global approach

VE Bianchi, S von Haehling - Clinical Research in Cardiology, 2023 - Springer
Chronic anemia is an independent risk factor for mortality in patients with heart failure (HF).
Restoring physiological hemoglobin (Hb) levels is essential to increase oxygen transport …

[HTML][HTML] Testosterone, gender identity and gender-stereotyped personality attributes

KV Casto, DJ Cohen, M Akinola, PH Mehta - Hormones and Behavior, 2024 - Elsevier
Sex/gender differences in personality associated with gender stereotyped behavior are
widely studied in psychology yet remain a subject of ongoing debate. Exposure to …

Androgens and Parkinson's disease: a review of human studies and animal models

M Bourque, D Soulet, T Di Paolo - Androgens: Clinical Research …, 2021 - liebertpub.com
Parkinson's disease (PD) is the second most common neurodegenerative disorder after
Alzheimer's disease. A greater prevalence and incidence of PD are reported in men than in …

Involvement of p38 MAPK in Leydig cell aging and age-related decline in testosterone

D Luo, X Qi, X Xu, L Yang, C Yu, Q Guan - Frontiers in Endocrinology, 2023 - frontiersin.org
Introduction Age-related decline in testosterone is associated with Leydig cell aging with
impaired testosterone synthesis in aging. Obesity accelerates the age-related decline in …

Relationship between testosterone and sarcopenia in older-adult men: a narrative review

K Shigehara, Y Kato, K Izumi, A Mizokami - Journal of Clinical Medicine, 2022 - mdpi.com
Age-related decline in testosterone is known to be associated with various clinical symptoms
among older men and it is possible that the accompanying decline in muscle mass and …

Testosterone, Sex, and Sport

KV Casto, JM Carré - … Insights from the Behavioral and Brain …, 2023 - journals.sagepub.com
Recent policies banning or limiting the participation of transgender and intersex women from
the women's category of sport have called upon the science of testosterone to justify …

Exogenous Nucleotides Ameliorate Age-Related Decline in Testosterone in Male Senescence-Accelerated Mouse Prone-8 (SAMP8) Mice by Modulating the Local …

Q Chen, R Liu, C Wei, X Wang, X Wu, R Fan, X Yu, Z Li… - Nutrients, 2023 - mdpi.com
In older men, an age-related decline in testosterone is closely associated with various
adverse health outcomes. With the progression of aging, hyperactivation of the local renin …