[HTML][HTML] Mechanisms of action of fluvoxamine for COVID-19: a historical review
Y Hashimoto, T Suzuki, K Hashimoto - Molecular psychiatry, 2022 - nature.com
The ongoing coronavirus disease 2019 (COVID-19) pandemic caused by the novel severe
acute respiratory syndrome coronavirus 2 (SARS-CoV-2) accelerates the discovery of …
acute respiratory syndrome coronavirus 2 (SARS-CoV-2) accelerates the discovery of …
A global picture: therapeutic perspectives for COVID-19
VP Chavda, C Kapadia, S Soni, R Prajapati… - …, 2022 - Future Medicine
The COVID-19 pandemic is a lethal virus outbreak by severe acute respiratory syndrome
coronavirus-2 (SARS-CoV-2), which has severely affected human lives and the global …
coronavirus-2 (SARS-CoV-2), which has severely affected human lives and the global …
[HTML][HTML] Continuous spatiotemporal therapy of a full-API nanodrug via multi-step tandem endogenous biosynthesis
Nanomedicine holds great promise to enhance cancer therapy. However, low active
pharmaceutical ingredient (API) loading content, unpredictable drug release, and potential …
pharmaceutical ingredient (API) loading content, unpredictable drug release, and potential …
[HTML][HTML] Antiviral drug discovery for the treatment of COVID-19 infections
TI Ng, I Correia, J Seagal, DA DeGoey, MR Schrimpf… - Viruses, 2022 - mdpi.com
The coronavirus disease 2019 (COVID-19) pandemic is caused by the severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2), a recently emerged human coronavirus …
respiratory syndrome coronavirus 2 (SARS-CoV-2), a recently emerged human coronavirus …
[HTML][HTML] Biomedical knowledge graph learning for drug repurposing by extending guilt-by-association to multiple layers
Computational drug repurposing aims to identify new indications for existing drugs by
utilizing high-throughput data, often in the form of biomedical knowledge graphs. However …
utilizing high-throughput data, often in the form of biomedical knowledge graphs. However …
[HTML][HTML] A multistage in silico study of natural potential inhibitors targeting SARS-CoV-2 main protease
Among a group of 310 natural antiviral natural metabolites, our team identified three
compounds as the most potent natural inhibitors against the SARS-CoV-2 main protease …
compounds as the most potent natural inhibitors against the SARS-CoV-2 main protease …
[HTML][HTML] Inhibitors of sars-cov-2 plpro
The emergence of SARS-CoV-2 causing the COVID-19 pandemic, has highlighted how a
combination of urgency, collaboration and building on existing research can enable rapid …
combination of urgency, collaboration and building on existing research can enable rapid …
[HTML][HTML] An interaction-based drug discovery screen explains known SARS-CoV-2 inhibitors and predicts new compound scaffolds
P Schake, K Dishnica, F Kaiser, C Leberecht… - Scientific Reports, 2023 - nature.com
The recent outbreak of the COVID-19 pandemic caused by severe acute respiratory
syndrome-Coronavirus-2 (SARS-CoV-2) has shown the necessity for fast and broad drug …
syndrome-Coronavirus-2 (SARS-CoV-2) has shown the necessity for fast and broad drug …
[HTML][HTML] A comprehensive review of drug repurposing strategies against known drug targets of COVID-19
Drug repurposing is a more inexpensive and shorter approach than the traditional drug
discovery and development process. The concept of identifying a potent molecule from a …
discovery and development process. The concept of identifying a potent molecule from a …
Drug repurposing for viral cancers: a paradigm of machine learning, deep learning, and virtual screening‐based approaches
Cancer management is major concern of health organizations and viral cancers account for
approximately 15.4% of all known human cancers. Due to large number of patients, efficient …
approximately 15.4% of all known human cancers. Due to large number of patients, efficient …