[HTML][HTML] Mesenchymal stem cell-derived exosomes as a new therapeutic strategy for liver diseases

G Lou, Z Chen, M Zheng, Y Liu - Experimental & molecular medicine, 2017 - nature.com
The administration of mesenchymal stem cells (MSCs) as a therapy for liver disease holds
great promise. MSCs can differentiate into hepatocytes, reduce liver inflammation, promote …

[HTML][HTML] Therapeutic properties of mesenchymal stromal/stem cells: the need of cell priming for cell-free therapies in regenerative medicine

V Miceli, M Bulati, G Iannolo, G Zito, A Gallo… - International Journal of …, 2021 - mdpi.com
Mesenchymal stromal/stem cells (MSCs) are multipotent adult stem cells that support
homeostasis during tissue regeneration. In the last decade, cell therapies based on the use …

Extracellular vesicles derived from mesenchymal stem/stromal cells: the regenerative impact in liver diseases

A Psaraki, L Ntari, C Karakostas, D Korrou‐Karava… - …, 2022 - Wiley Online Library
Liver dysfunctions are classified into acute and chronic diseases, which comprise a
heterogeneous group of pathological features and a high mortality rate. Liver transplantation …

Mesenchymal stromal cells in hepatic fibrosis/cirrhosis: from pathogenesis to treatment

X Yang, Q Li, W Liu, C Zong, L Wei, Y Shi… - Cellular & Molecular …, 2023 - nature.com
Hepatic fibrosis/cirrhosis is a significant health burden worldwide, resulting in liver failure or
hepatocellular carcinoma (HCC) and accounting for many deaths each year. The …

Mesenchymal stromal cell therapy for liver diseases

M Alfaifi, YW Eom, PN Newsome, SK Baik - Journal of hepatology, 2018 - Elsevier
The therapeutic potential of mesenchymal stromal cells (MSCs) in the treatment of liver
fibrosis is predominantly based on their immunosuppressive properties, and their ability to …

[HTML][HTML] Mesenchymal stromal cells (MSCs) and their exosome in acute liver failure (ALF): a comprehensive review

S Shokravi, V Borisov, BA Zaman, F Niazvand… - Stem Cell Research & …, 2022 - Springer
Recently, mesenchymal stromal cells (MSCs) and their derivative exosome have become a
promising approach in the context of liver diseases therapy, in particular, acute liver failure …

[HTML][HTML] 3D cell sheet structure augments mesenchymal stem cell cytokine production

S Bou-Ghannam, K Kim, DW Grainger, T Okano - Scientific reports, 2021 - nature.com
Mesenchymal stem cells (MSCs) secrete paracrine factors that play crucial roles during
tissue regeneration. An increasing body of evidence suggests that this paracrine function is …

Liver cirrhosis: An overview of experimental models in rodents

LAP Faccioli, ML Dias, BA Paranhos… - Life sciences, 2022 - Elsevier
The liver, a component of the gastrointestinal tract, is one of the most important organs in the
human body. The liver performs over 500 functions to promote physiological homeostasis. In …

Pre‐treatments enhance the therapeutic effects of mesenchymal stem cells in liver diseases

C Hu, Z Wu, L Li - Journal of Cellular and Molecular Medicine, 2020 - Wiley Online Library
Liver diseases caused by viral infection, alcohol abuse and metabolic disorders can
progress to end‐stage liver failure, liver cirrhosis and liver cancer, which are a growing …

Human menstrual blood-derived stem cells ameliorate liver fibrosis in mice by targeting hepatic stellate cells via paracrine mediators

L Chen, C Zhang, L Chen, X Wang… - Stem cells …, 2017 - academic.oup.com
Mesenchymal stem cells (MSCs) may have potential applications in regenerative medicine
for the treatment of chronic liver diseases (CLDs). Human menstrual blood is a novel source …