Nanomedicine combats drug resistance in lung cancer

X Zheng, X Song, G Zhu, D Pan, H Li, J Hu… - Advanced …, 2024 - Wiley Online Library
Lung cancer is the second most prevalent cancer and the leading cause of cancer‐related
death worldwide. Surgery, chemotherapy, molecular targeted therapy, immunotherapy, and …

[HTML][HTML] Peptide-based bioconjugates and therapeutics for targeted anticancer therapy

SB Yang, N Banik, B Han, DN Lee, J Park - Pharmaceutics, 2022 - mdpi.com
With rapidly growing knowledge in bioinformatics related to peptides and proteins, amino
acid-based drug-design strategies have recently gained importance in pharmaceutics. In the …

Albumin-modified gold nanoparticles as novel radiosensitizers for enhancing lung cancer radiotherapy

Y Chen, S Liu, Y Liao, H Yang, Z Chen… - International Journal …, 2023 - Taylor & Francis
Background Considering the strong attenuation of photons and the potential to increase the
deposition of radiation, high-atomic number nanomaterials are often used as …

[HTML][HTML] Strategies for efficient targeting of tumor collagen for cancer therapy

S Baldari, F Di Modugno, P Nisticò, G Toietta - Cancers, 2022 - mdpi.com
Simple Summary The tumor microenvironment encompasses the cellular and extracellular
matrix components that support and shape the three-dimensional framework in which solid …

Emerging natural polymer-based architectured nanotherapeutics for the treatment of cancer

K Kuna, SR Baddam, S Kalagara, PC Akkiraju… - International Journal of …, 2024 - Elsevier
The field of cancer therapy is advancing rapidly, placing a crucial emphasis on innovative
drug delivery systems. The increasing global impact of cancer highlights the need for …

[HTML][HTML] Drug delivery strategies for the treatment of pancreatic cancer

O Olajubutu, OD Ogundipe, A Adebayo, SK Adesina - Pharmaceutics, 2023 - mdpi.com
Pancreatic cancer is fast becoming a global menace and it is projected to be the second
leading cause of cancer-related death by 2030. Pancreatic adenocarcinomas, which …

In situ albumin-binding and esterase-specifically cleaved BRD4-degrading PROTAC for targeted cancer therapy

H Cho, SI Jeon, MK Shim, CH Ahn, K Kim - Biomaterials, 2023 - Elsevier
Proteolysis-targeting chimeras (PROTACs) have recently been of great interest in cancer
therapy. However, the bioavailability of PROTACs is considerably restricted due to their high …

Recent advances in nanotechnology for Intra-nasal drug delivery and clinical applications

G Rai, P Gauba, S Dang - Journal of Drug Delivery Science and …, 2023 - Elsevier
Nanotechnology has proved its tremendous worth in the field of drug delivery and targeting.
Nano formulations have improved the safety and efficacy of various conventional drugs …

Role of Albumin as a Targeted Drug Carrier in the Management of Rheumatoid Arthritis: A Comprehensive Review

U Garg, N Jain, S Kaul, U Nagaich - Molecular Pharmaceutics, 2023 - ACS Publications
An endogenous transporter protein called albumin interacts with the Fc receptor to provide it
with multiple substrate-binding domains, cell membrane receptor activation, and an …

[HTML][HTML] Supermagnetic human serum albumin (HSA) nanoparticles and PLGA-based doxorubicin nanoformulation: A duet for selective nanotherapy

J Malinovskaya, R Salami, M Valikhov… - International Journal of …, 2022 - mdpi.com
Predicting the ability of nanoparticles (NP) to access the tumor is key to the success of
chemotherapy using nanotherapeutics. In the present study, the ability of the dual NP-based …