[HTML][HTML] Mechanism and strategies of immunotherapy resistance in colorectal cancer

J Shan, D Han, C Shen, Q Lei, Y Zhang - Frontiers in immunology, 2022 - frontiersin.org
Colorectal cancer (CRC) is the third most common cancer in the world. Although there are
standard treatment options for CRC, most patients respond poorly to these treatments …

Long noncoding RNA URB1-antisense RNA 1 (AS1) suppresses sorafenib-induced ferroptosis in hepatocellular carcinoma by driving ferritin phase separation

Y Gao, M Tong, TL Wong, KY Ng, YN Xie, Z Wang… - ACS …, 2023 - ACS Publications
Sorafenib, a first-line molecular-target drug for advanced hepatocellular carcinoma (HCC),
has been shown to be a potent ferroptosis inducer in HCC. However, we found that there …

[HTML][HTML] Crosstalk between N6-methyladenosine (m6A) modification and noncoding RNA in tumor microenvironment

D Wang, Y Han, L Peng, T Huang, X He… - … Journal of Biological …, 2023 - ncbi.nlm.nih.gov
Abstract N6-methyladenosine (m6A) is the most abundant RNA modification in eukaryotes,
and it participates in the regulation of pathophysiological processes in various diseases …

[HTML][HTML] Oncofetal protein IGF2BPs in human cancer: functions, mechanisms and therapeutic potential

TY Zhu, LL Hong, ZQ Ling - Biomarker research, 2023 - Springer
Abstract N6-methyladenosine (m6A) is the most prevalent and well-characterized internal
chemical modification in eukaryotic RNA, influencing gene expression and phenotypic …

[HTML][HTML] LncRNA FIRRE functions as a tumor promoter by interaction with PTBP1 to stabilize BECN1 mRNA and facilitate autophagy

Y Wang, Z Li, S Xu, W Li, M Chen, M Jiang… - Cell death & disease, 2022 - nature.com
Long non-coding RNAs (lncRNAs) play critical functions in various cancers. Firre intergenic
repeating RNA element (FIRRE), a lncRNA located in the nucleus, was overexpressed in …

LncRNA signature in colorectal cancer

S Ghafouri-Fard, BM Hussen, A Gharebaghi… - … -Research and Practice, 2021 - Elsevier
Colorectal cancer (CRC) is among the most frequent cancers and is associated with high
mortality particularly when being diagnosed in advanced stages. Although several …

[HTML][HTML] N6-methyladenosine modification and metabolic reprogramming of digestive system malignancies

X Cai, C Liang, M Zhang, Y Xu, Y Weng, X Li, W Yu - Cancer Letters, 2022 - Elsevier
Abstract N 6-methyladenosine (m6A) is a eukaryotic post-transcriptional modification
involved in cell growth and developmental processes, including RNA transcription …

[HTML][HTML] lncRNA miR4458HG modulates hepatocellular carcinoma progression by activating m6A-dependent glycolysis and promoting the polarization of tumor …

Y Ye, M Wang, G Wang, Z Mai, B Zhou, Y Han… - Cellular and Molecular …, 2023 - Springer
Long non-coding RNAs (lncRNAs) play significant roles in different biological functions of
cancers. However, their function in the metabolism of glucose in patients with human …

Novel insights into the interaction between N6‐methyladenosine methylation and noncoding RNAs in musculoskeletal disorders

J Han, H Kong, X Wang, X Zhang - Cell Proliferation, 2022 - Wiley Online Library
Background Musculoskeletal disorder (MSD) are a class of inflammatory and degener‐ative
diseases, but the precise molecular mechanisms are still poorly understood. Noncoding …

[HTML][HTML] Long noncoding RNA DGCR5 involves in tumorigenesis of esophageal squamous cell carcinoma via SRSF1-mediated alternative splicing of Mcl-1

Y Duan, Y Jia, J Wang, T Liu, Z Cheng, M Sang… - Cell death & …, 2021 - nature.com
Long noncoding RNAs (lncRNAs) emerge as essential roles in the regulation of alternative
splicing (AS) in various malignancies. Serine-and arginine-rich splicing factor 1 (SRSF1) …